Comparison of Long-Term Outcomes in Early-Stage Endometrial Cancer: Robotic Single-Site vs. Multiport Laparoscopic Surgery

The purpose of this study was to establish the noninferiority of robotic single-site (RSS) surgery compared with multiport laparoscopic (MPL) surgery in surgical outcomes and overall survival for early endometrial cancer. This study was conducted retrospectively in a single center and included 421 p...

Full description

Saved in:
Bibliographic Details
Published in:Journal of personalized medicine 2024-06, Vol.14 (6), p.601
Main Authors: Kang, Heeju, Chung, Hyewon, Lee, Seungmee, Jang, Tae-Kyu, Shin, So-Jin, Kwon, Sang-Hoon, Cho, Chi-Heum
Format: Article
Language:English
Subjects:
Body mass index
Cancer
Cancer therapies
Diabetes
Endometrial cancer
Endometrium
Gynecology
Health aspects
Histopathology
Hypertension
Hysterectomy
Laparoscopic surgery
Laparoscopy
Laparotomy
Lymphatic system
Multivariate analysis
Obstetrics
Oophorectomy
Patients
Radiation therapy
Recovery (Medical)
Robotic surgery
Software
Statistical analysis
Survival
Survival analysis
Uterine cancer
Women
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose of this study was to establish the noninferiority of robotic single-site (RSS) surgery compared with multiport laparoscopic (MPL) surgery in surgical outcomes and overall survival for early endometrial cancer. This study was conducted retrospectively in a single center and included 421 patients who underwent either RSS ( = 146) or MPL ( = 275) surgery between 2014 and 2022. In terms of perioperative outcomes, the RSS group had a longer operating time than the MPL surgery group (mean (standard deviation [SD]) RSS 97.55 [29.79] vs. MPL 85.56 [26.13], < 0.001). However, no significant differences in estimated blood loss or perioperative complications were found between the groups ( = 0.196 and = 0.080, respectively). The patients in the RSS group were discharged earlier than those in the MPL group (mean [SD]): 4.06 [3.24] vs. 9.39 [4.76], < 0.001). Regarding oncologic outcomes, no significant differences in the type of therapy, disease stage, tumor grade, histopathological type, or lymphovascular invasion were found between the groups. No statistically significant differences were found in the disease-free ( = 0.27) and overall survival rates ( = 0.5) either. In conclusion, this study suggests that RSS and MPL surgery are both safe and effective options for staging operations in patients with early-stage endometrial cancer.
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm14060601