Clinical management of extra‑adrenal myelolipoma in the central nervous system: A case report

Extra-adrenal myelolipoma (EAM) is a rare benign tumor composed of mature adipose and hematopoietic tissues. Its etiology remains to be elucidated and there are few case reports describing the clinical features and treatment of EAMs in the central nervous system. The present study presented our expe...

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Bibliographic Details
Published in:Experimental and therapeutic medicine 2024-08, Vol.28 (2), Article 327
Main Authors: Xu, Zhijian, Yang, Song, Tu, Qi, Han, Peiyue, Wang, Lixia, Wang, Lude, Tong, Minfeng, Chen, Huahui
Format: Article
Language:English
Subjects:
Abdomen
Adipocytes
Adrenal glands
Analysis
Anemia
Autopsy
Body fat
Bone marrow
Breast cancer
Calcification
Care and treatment
Case Report
Case reports
Central nervous system
CT imaging
Diagnosis
Lung cancer
Magnetic resonance imaging
Medical examination
Nervous system
Pathology
Patients
Tumors
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Summary:Extra-adrenal myelolipoma (EAM) is a rare benign tumor composed of mature adipose and hematopoietic tissues. Its etiology remains to be elucidated and there are few case reports describing the clinical features and treatment of EAMs in the central nervous system. The present study presented our experience and practice in the clinical management of a case of EAM in the right frontal region. A 56-year-old woman was found to have a space-occupying right frontal lesion on computed tomography (CT) of the head. Unenhanced magnetic resonance imaging (MRI) showed a lesion of ~1.5*1.2 cm. Enhanced whole abdominal CT showed a right presacral mass, 2.0 cm in diameter, with clear margins. The postoperative histopathological findings showed mainly mature adipose tissue mixed with extramedullary hematopoietic components. This confirmed the diagnosis of a (bone) marrow lipoma. Myelolipoma of the central nervous system is extremely rare. to the best of the authors' knowledge, only two cases of intracranial myelolipoma have been reported, and the present study introduced the first case in a Chinese patient reported in English. However, when CT shows high density and MRI shows mixed density in the tumor area even without enhancement, the possibility of myelolipoma should be considered in the differential diagnosis. Key words: brain, central nervous system, tomography, myelolipoma, benign tumor
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2024.12616