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Metabolomics 2023 workshop report: moving toward consensus on best QA/QC practices in LC–MS-based untargeted metabolomics

Introduction During the Metabolomics 2023 conference, the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) presented a QA/QC workshop for LC–MS-based untargeted metabolomics. Objectives The Best Practices Working Group disseminated recent findings from community forums and discu...

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Bibliographic Details
Published in:Metabolomics 2024-07, Vol.20 (4), p.73, Article 73
Main Authors: Mosley, Jonathan D., Dunn, Warwick B., Kuligowski, Julia, Lewis, Matthew R., Monge, María Eugenia, Ulmer Holland, Candice, Vuckovic, Dajana, Zanetti, Krista A., Schock, Tracey B.
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Language:English
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Summary:Introduction During the Metabolomics 2023 conference, the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) presented a QA/QC workshop for LC–MS-based untargeted metabolomics. Objectives The Best Practices Working Group disseminated recent findings from community forums and discussed aspects to include in a living guidance document. Methods Presentations focused on reference materials, data quality review, metabolite identification/annotation and quality assurance. Results Live polling results and follow-up discussions offered a broad international perspective on QA/QC practices. Conclusions Community input gathered from this workshop series is being used to shape the living guidance document, a continually evolving QA/QC best practices resource for metabolomics researchers.
ISSN:1573-3890
1573-3882
1573-3890
DOI:10.1007/s11306-024-02135-w