Case Series: Pleomorphic adenoma in minor salivary gland [version 2; peer review: 1 approved, 1 approved with reservations]

• Published in: F1000 research 2024-01, Vol.13, p.243
• Main Authors: Samia, Meherzi, Amin, Khbou, Rihab, Omri, Afifa, Charfi
• Format: Article
• Language: English
• Subjects: Adenoma; Biopsy; Clinical Practice; Disease management; Exocrine glands; Lesions; Lip; Lymphatic system; Magnetic resonance imaging; Medical history; Middle age; Morphology; Mouth; Oral cancer; Parotid gland; Salivary gland; Tumors
• ISSN: 2046-1402; 2046-1402
• DOI: 10.12688/f1000research.146682.2

Abstract* Pleomorphic adenomas (PA) are the most prevalent benign salivary gland neoplasms. They may occur at any age, with a peak incidence between 40 and 60 years of age. They are more commonly observed in females (60%). These tumors can arise in both the major and minor salivary glands. Approximately 80% of these tumors are diagnosed in the parotid gland, whereas 10% arise in the minor salivary glands, mainly affecting the palates, followed by the lips and cheeks. This report describes two cases of unusual lesions that were diagnosed as (PA) in the minor salivary glands in our department via a review of the relevant literature. The first case involved an 83-year-old man who presented with a slow-growing swelling on the right side of the upper lip, and the second case involved a 45-year-old woman who presented with a slow-growing lesion on the palate. The presence of PA was confirmed histopathologically after surgical resection. Although relatively rare, PA is a benign lesion, the diagnosis of which must be known for appropriate therapeutic management.