Vasoactive peptides as biomarkers for the prediction of retinopathy of prematurity

Background Retinopathy of prematurity (ROP) is a major complication in preterm infants. We assessed if plasma levels of midregional pro-atrial natriuretic peptide (MR-proANP) and C-terminal pro-endothelin-1 (CT-proET1) serve as early markers for subsequent ROP development in preterm infants

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Bibliographic Details
Published in:Pediatric research 2024-06, Vol.95 (7), p.1868-1874
Main Authors: Neumann, Roland P., Gerull, Roland, Hasler, Pascal W., Wellmann, Sven, Schulzke, Sven M.
Format: Article
Language:English
Subjects:
Atrial Natriuretic Factor - blood
Biomarkers
Biomarkers - blood
Birth weight
Clinical
Clinical Research Article
Endothelin-1 - blood
Female
Gestational Age
Humans
Infant, Newborn
Infant, Premature - blood
Logistic Models
Male
Medicine
Medicine & Public Health
Newborn babies
Pediatric Surgery
Pediatrics
Peptide Fragments - blood
Peptides
Premature babies
Prospective Studies
Protein Precursors - blood
Regression analysis
Retinopathy of Prematurity - blood
Retinopathy of Prematurity - diagnosis
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Description
Summary:Background Retinopathy of prematurity (ROP) is a major complication in preterm infants. We assessed if plasma levels of midregional pro-atrial natriuretic peptide (MR-proANP) and C-terminal pro-endothelin-1 (CT-proET1) serve as early markers for subsequent ROP development in preterm infants
ISSN:0031-3998
1530-0447
1530-0447
DOI:10.1038/s41390-024-03091-w