Artemisinin-induced cholestatic liver injury and intrahepatic ductopenia

Artemisinin, an ancient Chinese herbal remedy known colloquially as "Qinghao", is now used as treatment for malaria as recommended by the World Health Organisation. There have been few reports of artemisinin-induced liver injury. Most of these instances of hepatotoxicity are reportedly due...

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Bibliographic Details
Published in:Oxford Medical Case Reports 2024-07, Vol.2024 (7), p.omae070
Main Authors: Thio, Joel, Haig, Adam, Swe, Ei Phyu Phyu, Nguyen, Paul, Tran, Kayla, Kasi, Madhavi
Format: Article
Language:English
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Case Report
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Summary:Artemisinin, an ancient Chinese herbal remedy known colloquially as "Qinghao", is now used as treatment for malaria as recommended by the World Health Organisation. There have been few reports of artemisinin-induced liver injury. Most of these instances of hepatotoxicity are reportedly due to prolonged use of herbal remedies containing artemisinin. To our knowledge, we report the first case of intrahepatic ductopenia in a patient with cholestatic liver injury after artemisinin use.
ISSN:2053-8855
2053-8855
DOI:10.1093/omcr/omae070