Relation between decline in FEV1 and exposure to dust and tobacco smoke in aluminium potroom workers

OBJECTIVES: To investigate the relation between pulmonary function and occupational exposure in aluminium pot operators. METHODS: 2795 observations were obtained in 630 workers over six years of follow up. An autoregressive method of analysis was used. RESULTS: After adjustment for FEV1 in the three...

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Bibliographic Details
Published in:Occupational and environmental medicine (London, England) England), 1997-01, Vol.54 (1), p.27-31
Main Authors: Søyseth, V, Boe, J, Kongerud, J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aluminum
Biological and medical sciences
Chemical and industrial products toxicology. Toxic occupational diseases
Chronic obstructive pulmonary disease
Confidence Intervals
Dust - adverse effects
Female
Fluorides
Fluorides - adverse effects
Forced Expiratory Volume - physiology
Humans
Longitudinal Studies
Lungs
Male
Mathematical independent variables
Medical sciences
Metallurgy
Metals and various inorganic compounds
Middle Aged
Modeling
Occupational Exposure - adverse effects
Particulate matter
Particulates
Regression Analysis
Respiration Disorders - etiology
Respiration Disorders - physiopathology
Respiratory function
Smoking - adverse effects
Smoking - physiopathology
Spirometry
Temporal logic
Tobacco smoking
Toxicology
Vital Capacity
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Summary:OBJECTIVES: To investigate the relation between pulmonary function and occupational exposure in aluminium pot operators. METHODS: 2795 observations were obtained in 630 workers over six years of follow up. An autoregressive method of analysis was used. RESULTS: After adjustment for FEV1 in the three previous years, the effect of smoking v no smoking on FEV1 was -43.1 ml, 95% confidence interval (95% CI) -72.3 to -13.9. Similarly, an increase in the exposure to particulates by 1 mg/m3 corresponded to a decrease in FEV1 of -11.9 ml, 95% CI -19.9 to -3.9. Age was a significant predictor of both FEV1 and FVC. CONCLUSION: Exposure to particulates in aluminium potrooms seems to increase the decline in FEV15 thereby increasing the risk of development of chronic obstructive lung disease in pot operators.
ISSN:1351-0711
1470-7926
DOI:10.1136/oem.54.1.27