Suspected Counterfeit M-30 Oxycodone Pill Exposures and Acute Withdrawals Reported from a Single Hospital - Toxicology Investigators Consortium Core Registry, U.S. Census Bureau Western Region, 2017-2022

Availability of counterfeit prescription pills (counterfeit pills) containing illegally made fentanyl, including counterfeit M-30 oxycodone (counterfeit M-30) pills, has risen sharply in the United States and has been increasingly linked to overdose deaths. In 2023, approximately 115 million counter...

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Published in:MMWR. Morbidity and mortality weekly report 2024-07, Vol.73 (29), p.642-647
Main Authors: Glidden, Emily, Gladden, R Matthew, Dion, Chris, Spyres, Meghan B, Seth, Puja, Aldy, Kim, Mustaquim, Desiree
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Amphetamines
Analysis
Benzodiazepines
Censuses
Central nervous system depressants
Child
Cocaine
Consortia
Counterfeit
Counterfeit Drugs
Counterfeiting
Drug counterfeiting
Drug dealing
Drug Overdose
Drug traffic
Drug trafficking
Drug withdrawal
Drugs
Evidence-based medicine
Exposure
Female
Fentanyl
Full Report
Harm reduction
Hospital patients
Hospitals
Humans
Intensive care
Male
Medical laboratories
Methamphetamine
Middle Aged
Narcotics
Overdose
Oxycodone
Oxycodone - poisoning
Patients
Pharmacists
Prescription drugs
Public health
Registries
Substance abuse
Substance use
Substance Withdrawal Syndrome
Toxicity
Toxicology
United States
Young Adult
Young adults
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container_end_page 647
container_issue 29
container_start_page 642
container_title MMWR. Morbidity and mortality weekly report
container_volume 73
creator Glidden, Emily
Gladden, R Matthew
Dion, Chris
Spyres, Meghan B
Seth, Puja
Aldy, Kim
Mustaquim, Desiree
description Availability of counterfeit prescription pills (counterfeit pills) containing illegally made fentanyl, including counterfeit M-30 oxycodone (counterfeit M-30) pills, has risen sharply in the United States and has been increasingly linked to overdose deaths. In 2023, approximately 115 million counterfeit pills were seized in U.S. High Intensity Drug Trafficking Areas. However, clinical data on counterfeit pill-related overdoses are limited. Medical toxicology consultations during 2017-2022 from one U.S. Census Bureau Western Region hospital participating in the Toxicology Investigators Consortium Core Registry were analyzed. A total of 352 cases suspected to involve counterfeit M-30 pills, including 143 (40.6%) cases of fentanyl exposure and 209 (59.4%) cases of acute withdrawal were identified; consultations increased from three in 2017, to 209 in 2022. Patients aged 15-34 years accounted for 95 (67.4%) exposure cases. Among all patients with exposures, 81.1% were hospitalized, 69.0% of whom were admitted to an intensive care unit. Additional substances were detected in 131 (91.6%) exposures. Providing outreach to younger persons misusing prescription pills, improving access to and distribution of harm reduction tools including fentanyl test strips and naloxone, and promoting linkage of persons treated for overdose in hospitals to harm reduction and substance use treatment services are strategies to reduce morbidity associated with use of counterfeit M-30.
doi_str_mv 10.15585/mmwr.mm7329a2
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subjects Adolescent
Adult
Aged
Amphetamines
Analysis
Benzodiazepines
Censuses
Central nervous system depressants
Child
Cocaine
Consortia
Counterfeit
Counterfeit Drugs
Counterfeiting
Drug counterfeiting
Drug dealing
Drug Overdose
Drug traffic
Drug trafficking
Drug withdrawal
Drugs
Evidence-based medicine
Exposure
Female
Fentanyl
Full Report
Harm reduction
Hospital patients
Hospitals
Humans
Intensive care
Male
Medical laboratories
Methamphetamine
Middle Aged
Narcotics
Overdose
Oxycodone
Oxycodone - poisoning
Patients
Pharmacists
Prescription drugs
Public health
Registries
Substance abuse
Substance use
Substance Withdrawal Syndrome
Toxicity
Toxicology
United States
Young Adult
Young adults
title Suspected Counterfeit M-30 Oxycodone Pill Exposures and Acute Withdrawals Reported from a Single Hospital - Toxicology Investigators Consortium Core Registry, U.S. Census Bureau Western Region, 2017-2022
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