Bowel Obstruction as the Initial Presentation of Urothelial Carcinoma

• Published in: Curēus (Palo Alto, CA) CA), 2024-07, Vol.16 (7), p.e64056
• Main Authors: Girão de Caires, Francisco, Nunes, Mafalda, Flores, Priscila, Girão de Caires, António, Dionísio, Isabel
• Format: Article
• Language: English
• Subjects: Abdomen; Adrenal glands; Anemia; Bladder cancer; Colon; Colonoscopy; Emergency medical care; Endoscopy; Fistula; General Surgery; Hematuria; Hernias; Intestinal obstruction; Kidney diseases; Lymphatic system; Medical imaging; Medical prognosis; Metastasis; Pathology; Small intestine; Tumors; Urology
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.64056

Bowel obstructions are one of the main causes of hospital admissions for acute abdominal pain. In addition, bladder cancer is one of the most common cancers in the world. This said, bowel obstruction and bladder cancer are very frequent diseases but the same cannot be said about the association between these two pathologies. We report a unique case of an 80-year-old patient admitted to the emergency room with a bowel obstruction caused by a urothelial carcinoma with adrenal metastasis. The patient underwent an urgent laparotomy, and intraoperative inspection of the peritoneal cavity confirmed a large tumorous mass suspected of gastrointestinal etiology. The mass infiltrated the ileum and sigmoid colon and was apparently in contact with the bladder wall. An en-bloc resection of the lesion was performed. An R0 excison was not possible and fragments of the lesion were excised from the bladder wall for separate analysis. Histopathological examination of the resected specimen described a high-grade, undifferentiated urothelial carcinoma that originated in the bladder and invaded the ileum and sigmoid colon. The presence of an invasive urothelial carcinoma presenting with bowel obstruction represents an unexpected diagnosis and, although rare, the surgeon must be aware of this possibility. This case should serve as a reminder that a broad differential diagnosis should be considered when investigating an abdominal tumor.