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Pregnancy characteristics in Egyptian female patients with NMOSD

Background Neuromyelitis optica spectrum disorder (NMOSD) primarily affects women of childbearing age. Objectives Studying the potential relationship between NMOSD and pregnancy characteristics and outcomes. Subjects and methods This is a retrospective cohort study that was conducted on 66 married f...

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Bibliographic Details
Published in:Multiple sclerosis journal - experimental, translational and clinical translational and clinical, 2024-07, Vol.10 (3), p.20552173241271878
Main Authors: Gad, Adel Hassanein, Kishk, Nirmeen, Shalaby, Nevin M, Heikal, Eman Salah, Fouad, Amr Mohamed, Merghany, Nahla, Abdelghany, Hend
Format: Article
Language:English
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Summary:Background Neuromyelitis optica spectrum disorder (NMOSD) primarily affects women of childbearing age. Objectives Studying the potential relationship between NMOSD and pregnancy characteristics and outcomes. Subjects and methods This is a retrospective cohort study that was conducted on 66 married female patients diagnosed with NMOSD. All patients underwent a thorough review of their demographic and clinical history through their medical records and personal interviews. Additionally, a complete neurological examination was performed, along with the expanded disability status scale (EDSS) and a pregnancy registry questionnaire. Results After comparing married patients before and after disease onset, there was a significant increase in the number of abortions and the percentage of cesarean sections, as well as a decrease in the percentage of breastfeeding after disease onset. The p values were .02,
ISSN:2055-2173
2055-2173
DOI:10.1177/20552173241271878