Anemia among adult patients with diabetes attending King Abdulaziz University Hospital: A retrospective study

• Published in: Medicine (Baltimore) 2024-08, Vol.103 (33), p.e39383
• Main Authors: Ghamri, Ranya, Salawati, Emad, Edrees, Ghalia W, Alsaleh, Aljawhara K, Srouji, Aya F, Radi, Tala O, Feteih, Maha M, Kary, Malak S, Altalhi, Rahaf J, Almanasif, Mersal A, Ahmed, Ferdous A
• Format: Article
• Language: English
• Subjects: Adult; Aged; Anemia - blood; Anemia - epidemiology; Anemia - etiology; Body Mass Index; Diabetes Mellitus - blood; Diabetes Mellitus - epidemiology; Female; Ferritins - blood; Glycated Hemoglobin - analysis; Hemoglobins - analysis; Hospitals, University; Humans; Iron - blood; Male; Middle Aged; Observational Study; Prevalence; Retrospective Studies; Saudi Arabia - epidemiology; Thyrotropin - blood
• ISSN: 1536-5964; 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000039383

The prevalence of anemia in adults with diabetes is of growing importance due to its impact on overall health and the management of diabetes-related complications. This study aimed to determine the prevalence of anemia among adult patients with diabetes at King Abdulaziz University Hospital in Jeddah, Saudi Arabia. A retrospective study was done on 1208 patients with diabetes >18 years who attended the study setting from 2010 to 2022. Data about patients' demographics, body mass index, glycated hemoglobin (HbA1c; %), hemoglobin (Hb), serum ferritin, iron, mean corpuscular Hb, mean corpuscular volume, free thyroxine and triiodothyronine (T3), and serum thyroid-stimulating hormone (TSH) were collected. Of patients, 86.6% had anemia with a prevalence of 30.2%, 47.6%, and 22.2% for mild, moderate, and severe anemias, respectively. The prevalence of anemia was significantly higher among females, those with high serum ferritin, normal serum iron or normal serum T3, lower mean HbA1c level (%), lower serum iron or T3, and higher serum ferritin or TSH. A significant positive correlation was found between Hb level and HbA1c level (%), serum iron, free T3, and body mass index. A significant negative correlation was found between Hb level and mean corpuscular volume, serum ferritin, and serum TSH. Being female, having high serum ferritin, lower mean free T3, and a high TSH were risk factors for anemia. The prevalence of severe anemia was significantly higher among patients with uncontrolled diabetes mellitus. A high prevalence of anemia was found among studied diabetics. Anemia screening should be included in the routine assessment of patients with diabetes. A multidisciplinary approach involving endocrinologists, hematologists, and dietitians is recommended to ensure holistic care and address all aspects of the patient's health. In addition, further research should be supported to better understand the mechanisms linking diabetes and anemia and to establish evidence-based guidelines for managing anemia in diabetics.