Differential display analysis of gene expression in invertebrates

Screening for differentially expressed genes is a straightforward approach to study the molecular basis for changes in gene expression. Differential display analysis has been used by investigators in diverse fields of research since it was developed. Differential display has also been the approach o...

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Bibliographic Details
Published in:Cellular and molecular life sciences : CMLS 2002-08, Vol.59 (8), p.1256-1263
Main Authors: Liao, V H C, Freedman, J H
Format: Article
Language:English
Subjects:
Animals
Cadmium
Cadmium - metabolism
Caenorhabditis elegans - genetics
Caenorhabditis elegans - physiology
Gene expression
Gene Expression Profiling
Gene Expression Regulation
Invertebrates
Invertebrates - genetics
Molecular biology
Nematodes
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Summary:Screening for differentially expressed genes is a straightforward approach to study the molecular basis for changes in gene expression. Differential display analysis has been used by investigators in diverse fields of research since it was developed. Differential display has also been the approach of choice to investigate changes in gene expression in response to various biological challenges in invertebrates. We review the application of differential display analysis of gene expression in invertebrates, and provide a specific example using this technique for novel gene discovery in the nematode Caenorhabditis elegans.
ISSN:1420-682X
1420-9071
DOI:10.1007/s00018-002-8504-9