Association Between Biologic Exposure and the Risk of Depression in Patients with Psoriasis: A Retrospective Analysis of Large US Administrative Claims Data

The cohorts were matched using the propensity score based on age at the index date, sex, geographical region, calendar year of index, Charlson Comorbidity Index category, baseline presence of commonly occurring comorbidities of interest (i.e., psoriatic arthritis, chronic pain, and anxiety), and bas...

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Bibliographic Details
Published in:American journal of clinical dermatology 2024-09, Vol.25 (5), p.853-856
Main Authors: Strober, Bruce, Soliman, Ahmed M., Truong, Bang, Patel, Manish B., Barqawi, Yazan K., Gisondi, Paolo
Format: Article
Language:English
Subjects:
Adult
Aged
Biological products
Biological Products - adverse effects
Biological Products - therapeutic use
Comorbidity
Depression - epidemiology
Depression - etiology
Dermatology
Disease
Female
Humans
Insomnia
Male
Medicine
Medicine & Public Health
Mental depression
Middle Aged
Pharmacology/Toxicology
Pharmacotherapy
Psoriasis
Psoriasis - epidemiology
Psoriasis - psychology
Psoriatic arthritis
Research Letter
Retrospective Studies
Risk Factors
Stock options
TNF inhibitors
Tumor necrosis factor-TNF
United States - epidemiology
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Description
Summary:The cohorts were matched using the propensity score based on age at the index date, sex, geographical region, calendar year of index, Charlson Comorbidity Index category, baseline presence of commonly occurring comorbidities of interest (i.e., psoriatic arthritis, chronic pain, and anxiety), and baseline total healthcare costs. [...]patients with psoriasis who initiated biologic versus csDMARD treatment had a lower incidence and risk of depression. AbbVie participated in the study design, research, interpretation of the data, review, and approval. AMS and BT made substantial contributions to the study conception and design and acquisition of data.
ISSN:1175-0561
1179-1888
1179-1888
DOI:10.1007/s40257-024-00877-w