Unmet Need in Early-Onset Parkinson’s Disease: Deep Brain Stimulation and Pregnancy

Pregnancy in women with early-onset Parkinson’s disease (PD) is likely to have a higher frequency given the trend toward increasing maternal age, thus resulting in a greater overlap time between childbearing age and PD risk. Deep brain stimulation (DBS) therapy is nowadays offered to PD patients at...

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Bibliographic Details
Published in:Journal of Parkinson's disease 2024-01, Vol.14 (6), p.1277-1282
Main Authors: Smilowska, Katarzyna, Mehanna, Raja, Fleisher, Jori E., Alcalay, Roy N., Kumar, Kishore Raj, Marras, Connie, Oosterbaan, Annelien M., Post, Bart, Ross, Owen A., Pimentel Piemonte, Maria Elisa, Fraix, Valerie, Moro, Elena, King Tan, Eng, Savica, Rodolfo
Format: Article
Language:English
Subjects:
Age
Deep brain stimulation
Movement disorders
Neurodegenerative diseases
Parkinson's disease
Pregnancy
Premenopause
Short Communication
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Summary:Pregnancy in women with early-onset Parkinson’s disease (PD) is likely to have a higher frequency given the trend toward increasing maternal age, thus resulting in a greater overlap time between childbearing age and PD risk. Deep brain stimulation (DBS) therapy is nowadays offered to PD patients at earlier stage of the disease, when women can still be pre-menopausal. However, few data are available about DBS safety during pregnancy. From a review of the available literature, only one article was published on this topic so far. Therefore, we have developed a clinical consensus on the safety of DBS during pregnancy in PD patients.
ISSN:1877-7171
1877-718X
DOI:10.3233/JPD-240088