An Infrequent Histopathological Diagnosis in a Prevalent Systemic Disease: A Case of Renal Sarcoidosis

Sarcoidosis is a multisystemic granulomatous disease that results from an aberrant immunological response to certain antigens. Although pulmonary involvement predominates, renal involvement may also occur. We present the case of a 59-year-old woman with a recent diagnosis of hepatic sarcoidosis and...

Full description

Saved in:
Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-08, Vol.16 (8), p.e66633
Main Authors: Reis Santos, Sónia, Cunha Rodrigues, Ana, Melo Pereira, José Luís, Costa, Marta, Domingues, Nelson
Format: Article
Language:English
Subjects:
Anemia
Antibodies
Biopsy
Brucellosis
Case reports
Creatinine
Enzymes
Granulomas
Hemoglobin
Hepatitis
Hypercalcemia
Immunology
Internal Medicine
Kidney diseases
Lungs
Medical diagnosis
Metabolism
Necrosis
Nephrology
Pathology
Patients
Rheumatology
Sarcoidosis
Steroids
Systemic diseases
Urine
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sarcoidosis is a multisystemic granulomatous disease that results from an aberrant immunological response to certain antigens. Although pulmonary involvement predominates, renal involvement may also occur. We present the case of a 59-year-old woman with a recent diagnosis of hepatic sarcoidosis and a history of non-compliance with treatment who was admitted to the hospital for study of acute kidney injury. Renal dysfunction was assumed to be a result of acute interstitial nephritis, as revealed on renal biopsy, and alterations in glomerular hemodynamics due to hypercalcemia. Renal function recovered and serum calcium levels normalized with the introduction of corticosteroid therapy.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.66633