Interventricular septum involvement is related to right ventricular dysfunction in anterior STEMI patients without right ventricular infarction: a cardiovascular magnetic resonance study

• Published in: The international journal of cardiovascular imaging 2024-08, Vol.40 (8), p.1755-1765
• Main Authors: Liang, Shichu, Chen, Shi, Bai, Yanlin, Ma, Min, Shi, Fanfan, Huang, Litao, Wang, Hua, Xia, Chunchao, Diao, Kaiyue, He, Yong
• Format: Article
• Language: English
• Subjects: Aged; Anterior Wall Myocardial Infarction - complications; Anterior Wall Myocardial Infarction - diagnostic imaging; Anterior Wall Myocardial Infarction - physiopathology; Anterior Wall Myocardial Infarction - therapy; Cardiac Imaging; Cardiology; Cerebral infarction; Confidence intervals; Female; Heart; Humans; Imaging; Magnetic resonance; Magnetic Resonance Imaging, Cine; Male; Medicine; Medicine & Public Health; Middle Aged; Myocardial infarction; Myocardium; Original Paper; Percutaneous Coronary Intervention; Performance prediction; Predictive Value of Tests; Prospective Studies; Radiology; Regression analysis; Risk Factors; Septum; ST Elevation Myocardial Infarction - complications; ST Elevation Myocardial Infarction - diagnostic imaging; ST Elevation Myocardial Infarction - physiopathology; ST Elevation Myocardial Infarction - therapy; Statistical analysis; Stroke Volume; Ventricle; Ventricular Dysfunction, Right - diagnostic imaging; Ventricular Dysfunction, Right - etiology; Ventricular Dysfunction, Right - physiopathology; Ventricular Function, Left; Ventricular Function, Right; Ventricular Septum - diagnostic imaging; Ventricular Septum - physiopathology
• ISSN: 1875-8312; 1569-5794; 1875-8312; 1573-0743
• DOI: 10.1007/s10554-024-03166-z

The value of cardiovascular magnetic resonance (CMR) in assessing and predicting acute right ventricular (RV) dysfunction in patients with anterior ST-segment elevation myocardial infarction (STEMI) remains ascertained. Eighty eight patients with anterior STEMI were prospectively recruited and underwent CMR examinations within one week following the coronary intervention. Patients with RV ejection fraction (RVEF) less than 2 standard deviations below the average at the center (RVEF ≤ 45.0%) were defined as having RV dysfunction. The size of infarction, segmental wall motion, and T1 and T2 mapping values of global myocardium and the interventricular septum (IVS) were measured. Predictive performance was calculated using receiver-operating characteristic curve analysis and logistic regression test. Twenty two patients presented with RV dysfunction. The RV dysfunction group had a larger IVS infarct extent (54.28 ± 10.35 vs 33.95 ± 15.09%, P