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Spectrum of [18F]FDG PET/CT Findings in Primary Central Nervous System Lymphoma - A Pictorial Essay
Primary central nervous system lymphoma (PCNSL) is a rare, aggressive variant of extranodal non-Hodgkin's lymphoma. Although gadolinium-enhanced magnetic resonance imaging remains the initial imaging modality of choice, a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography-com...
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Published in: | Indian journal of nuclear medicine 2024-05, Vol.39 (3), p.191-197 |
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creator | Nithya, V Valaiyapathy, N C Hemalatha, Dhamarcherla S Ramya Priya, Rallapeta Bhargavi, D Kalawat, Tekchand |
description | Primary central nervous system lymphoma (PCNSL) is a rare, aggressive variant of extranodal non-Hodgkin's lymphoma. Although gadolinium-enhanced magnetic resonance imaging remains the initial imaging modality of choice, a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography is imperative to exclude systemic lymphomatous involvement. Furthermore, the metabolic parameter, maximum standardized uptake value (SUV
) of the lesion, tumor-to-normal cerebral tissue SUV
ratio, and FDG uptake patterns help in differentiating intracranial lymphomas from High-grade Glioblastoma Multiforme (HGM) and infectious lesions, and hence, consolidating the diagnosis. In this pictorial essay, we present a series of PCNSL cases, representing the different imaging characteristics and metabolic uptake patterns. |
doi_str_mv | 10.4103/ijnm.ijnm_21_24 |
format | article |
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) of the lesion, tumor-to-normal cerebral tissue SUV
ratio, and FDG uptake patterns help in differentiating intracranial lymphomas from High-grade Glioblastoma Multiforme (HGM) and infectious lesions, and hence, consolidating the diagnosis. In this pictorial essay, we present a series of PCNSL cases, representing the different imaging characteristics and metabolic uptake patterns.</description><identifier>ISSN: 0972-3919</identifier><identifier>EISSN: 0974-0244</identifier><identifier>DOI: 10.4103/ijnm.ijnm_21_24</identifier><identifier>PMID: 39291062</identifier><language>eng</language><publisher>India: Medknow Publications & Media Pvt. Ltd</publisher><subject>Central nervous system ; Computed tomography ; Fluorine isotopes ; Gadolinium ; Lesions ; Magnetic resonance imaging ; Medical imaging ; Pictorial ; Positron emission ; Radioisotopes</subject><ispartof>Indian journal of nuclear medicine, 2024-05, Vol.39 (3), p.191-197</ispartof><rights>Copyright: © 2024 Indian Journal of Nuclear Medicine.</rights><rights>2024. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright: © 2024 Indian Journal of Nuclear Medicine 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c260t-fce83520407e13bdb8e8c2d7fccc0c6614d0e929401b22c5e273fcc0a42711fc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404745/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11404745/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39291062$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nithya, V</creatorcontrib><creatorcontrib>Valaiyapathy, N C</creatorcontrib><creatorcontrib>Hemalatha, Dhamarcherla S</creatorcontrib><creatorcontrib>Ramya Priya, Rallapeta</creatorcontrib><creatorcontrib>Bhargavi, D</creatorcontrib><creatorcontrib>Kalawat, Tekchand</creatorcontrib><title>Spectrum of [18F]FDG PET/CT Findings in Primary Central Nervous System Lymphoma - A Pictorial Essay</title><title>Indian journal of nuclear medicine</title><addtitle>Indian J Nucl Med</addtitle><description>Primary central nervous system lymphoma (PCNSL) is a rare, aggressive variant of extranodal non-Hodgkin's lymphoma. Although gadolinium-enhanced magnetic resonance imaging remains the initial imaging modality of choice, a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography is imperative to exclude systemic lymphomatous involvement. Furthermore, the metabolic parameter, maximum standardized uptake value (SUV
) of the lesion, tumor-to-normal cerebral tissue SUV
ratio, and FDG uptake patterns help in differentiating intracranial lymphomas from High-grade Glioblastoma Multiforme (HGM) and infectious lesions, and hence, consolidating the diagnosis. In this pictorial essay, we present a series of PCNSL cases, representing the different imaging characteristics and metabolic uptake patterns.</description><subject>Central nervous system</subject><subject>Computed tomography</subject><subject>Fluorine isotopes</subject><subject>Gadolinium</subject><subject>Lesions</subject><subject>Magnetic resonance imaging</subject><subject>Medical imaging</subject><subject>Pictorial</subject><subject>Positron emission</subject><subject>Radioisotopes</subject><issn>0972-3919</issn><issn>0974-0244</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kUtLAzEURoMotj7W7iTgeuzNY5LOSkptVShasK5EwkwmoymdSU1mCv33Tm19bdzkBu65Hwc-hM4IXHICrGfnVXm5eRQlivI91IVE8ggo5_uffxqxhCQddBTCHEBwKcQh6rCEJgQE7SL9uDS69k2JXYGfSX_8Mr6-wdPRrDec4bGtclu9BmwrPPW2TP0aD01V-3SB741fuSbgx3WoTYkn63L55soUR3iAp1bXztuWGoWQrk_QQZEugjndzWP0NB7NhrfR5OHmbjiYRJoKqKNCmz6LKXCQhrAsz_qmr2kuC601aCEIz8G04hxIRqmODZWs3UHKqSSk0OwYXW1zl01WmlxvTdVya65catXfTWXf1KtbKUI4cMnjNuFil-Dde2NCreau8VUrrRjhNJYCpPifarMEFYy0VG9Lae9C8Kb4FiGgNuWpz95-ymsvzn_7f_NfbbEPIJqWlg</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Nithya, V</creator><creator>Valaiyapathy, N C</creator><creator>Hemalatha, Dhamarcherla S</creator><creator>Ramya Priya, Rallapeta</creator><creator>Bhargavi, D</creator><creator>Kalawat, Tekchand</creator><general>Medknow Publications & Media Pvt. Ltd</general><general>Wolters Kluwer - Medknow</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>5PM</scope></search><sort><creationdate>20240501</creationdate><title>Spectrum of [18F]FDG PET/CT Findings in Primary Central Nervous System Lymphoma - A Pictorial Essay</title><author>Nithya, V ; Valaiyapathy, N C ; Hemalatha, Dhamarcherla S ; Ramya Priya, Rallapeta ; Bhargavi, D ; Kalawat, Tekchand</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c260t-fce83520407e13bdb8e8c2d7fccc0c6614d0e929401b22c5e273fcc0a42711fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Central nervous system</topic><topic>Computed tomography</topic><topic>Fluorine isotopes</topic><topic>Gadolinium</topic><topic>Lesions</topic><topic>Magnetic resonance imaging</topic><topic>Medical imaging</topic><topic>Pictorial</topic><topic>Positron emission</topic><topic>Radioisotopes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nithya, V</creatorcontrib><creatorcontrib>Valaiyapathy, N C</creatorcontrib><creatorcontrib>Hemalatha, Dhamarcherla S</creatorcontrib><creatorcontrib>Ramya Priya, Rallapeta</creatorcontrib><creatorcontrib>Bhargavi, D</creatorcontrib><creatorcontrib>Kalawat, Tekchand</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nithya, V</au><au>Valaiyapathy, N C</au><au>Hemalatha, Dhamarcherla S</au><au>Ramya Priya, Rallapeta</au><au>Bhargavi, D</au><au>Kalawat, Tekchand</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Spectrum of [18F]FDG PET/CT Findings in Primary Central Nervous System Lymphoma - A Pictorial Essay</atitle><jtitle>Indian journal of nuclear medicine</jtitle><addtitle>Indian J Nucl Med</addtitle><date>2024-05-01</date><risdate>2024</risdate><volume>39</volume><issue>3</issue><spage>191</spage><epage>197</epage><pages>191-197</pages><issn>0972-3919</issn><eissn>0974-0244</eissn><abstract>Primary central nervous system lymphoma (PCNSL) is a rare, aggressive variant of extranodal non-Hodgkin's lymphoma. Although gadolinium-enhanced magnetic resonance imaging remains the initial imaging modality of choice, a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography is imperative to exclude systemic lymphomatous involvement. Furthermore, the metabolic parameter, maximum standardized uptake value (SUV
) of the lesion, tumor-to-normal cerebral tissue SUV
ratio, and FDG uptake patterns help in differentiating intracranial lymphomas from High-grade Glioblastoma Multiforme (HGM) and infectious lesions, and hence, consolidating the diagnosis. In this pictorial essay, we present a series of PCNSL cases, representing the different imaging characteristics and metabolic uptake patterns.</abstract><cop>India</cop><pub>Medknow Publications & Media Pvt. Ltd</pub><pmid>39291062</pmid><doi>10.4103/ijnm.ijnm_21_24</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Central nervous system Computed tomography Fluorine isotopes Gadolinium Lesions Magnetic resonance imaging Medical imaging Pictorial Positron emission Radioisotopes |
title | Spectrum of [18F]FDG PET/CT Findings in Primary Central Nervous System Lymphoma - A Pictorial Essay |
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