Hypersensitivity to carbamazepine presenting as pseudolymphoma

An unusually severe hypersensitivity reaction to carbamazepine is described, in which the patient presented with lymphadenopathy, hepatosplenomegaly, bone marrow suppression, immunosuppression and other features strongly suggestive of a lymphoma.

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Bibliographic Details
Published in:Journal of clinical pathology 1986-11, Vol.39 (11), p.1224-1228
Main Authors: Yates, P, Stockdill, G, McIntyre, M
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Carbamazepine - adverse effects
Diagnosis, Differential
Drug Hypersensitivity - diagnosis
Drug Hypersensitivity - etiology
Drug toxicity and drugs side effects treatment
Humans
Lymph Nodes - pathology
Lymphatic Diseases - chemically induced
Lymphatic Diseases - diagnosis
Lymphatic Diseases - pathology
Lymphoma - diagnosis
Male
Medical sciences
Miscellaneous (drug allergy, mutagens, teratogens...)
Pharmacology. Drug treatments
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Description
Summary:An unusually severe hypersensitivity reaction to carbamazepine is described, in which the patient presented with lymphadenopathy, hepatosplenomegaly, bone marrow suppression, immunosuppression and other features strongly suggestive of a lymphoma.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.39.11.1224