Normal Saline or Sodium Hypochlorite Irrigation for Vital Pulp Therapy? A Non-Inferiority Randomized Controlled Trial

criteria were randomized to each irrigant, 65 in the NaOCl and 60 in the NSS groups. ProRoot® MTA was used as a pulp dressing material in both groups and teeth were followed for 12 months. The primary outcome was the success of VPT; requiring both clinical and radiographic success to be considered a...

Full description

Saved in:
Bibliographic Details
Published in:European endodontic journal 2024-08, Vol.9 (3), p.180-190
Main Authors: Machareonsap, Hataichanok, Chompu-Inwai, Papimon, Chaipattanawan, Nattakan, Manmontri, Chanika, Nirunsittirat, Areerat, Phinyo, Phichayut
Format: Article
Language:English
Subjects:
Adult
Aluminum Compounds
Calcium Compounds - administration & dosage
Drug Combinations
Female
Humans
Male
Middle Aged
Original
Oxides
Root Canal Irrigants
Root Canal Therapy - methods
Saline Solution - administration & dosage
Silicates
Sodium Hypochlorite - pharmacology
Therapeutic Irrigation - methods
Tooth Discoloration
Treatment Outcome
Young Adult
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:criteria were randomized to each irrigant, 65 in the NaOCl and 60 in the NSS groups. ProRoot® MTA was used as a pulp dressing material in both groups and teeth were followed for 12 months. The primary outcome was the success of VPT; requiring both clinical and radiographic success to be considered as success. The hypothesis was that the absolute difference of VPT success in the NSS group was not worse than that in the NaOCl group, by a margin of 5%. The secondary outcome was discoloration; percentages of discolorations between both groups were compared. Results: Using a per protocol analysis, the absolute difference of VPT success between the NSS and NaOCl groups was 2.08% (95% CI: -1.95, 6.1). Perceptible gray discolorations were 80% and 63% in NaOCl and NSS groups (difference -17%; 95% CI: -40.0, 6.2; p=0.15). Conclusions: For MTA-VPT procedure, irrigation with NSS was not worse than that with NaOCl. However, both irrigants caused discoloration. (EEJ-2023-05-065).
ISSN:2548-0839
2548-0839
DOI:10.14744/eej.2023.30932