Microwave irradiation of human brain tissue: production of microscopic slides within one day

A three step method using microwave irradiation enabled microscopic slides of human brain tissue to be obtained within one working day: steps 1 and 2 hardened and solidified brain tissue; step 3 completed formalin fixation. The efficacy and precision of the method was compared with slides of convent...

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Bibliographic Details
Published in:Journal of clinical pathology 1988-05, Vol.41 (5), p.590-593
Main Authors: Boon, M E, Marani, E, Adriolo, P J, Steffelaar, J W, Bots, G T, Kok, L P
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Brain - pathology
Female
Histological Techniques
Humans
Male
Microwaves
Middle Aged
Time Factors
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Summary:A three step method using microwave irradiation enabled microscopic slides of human brain tissue to be obtained within one working day: steps 1 and 2 hardened and solidified brain tissue; step 3 completed formalin fixation. The efficacy and precision of the method was compared with slides of conventionally processed brain tissue that had been fixed in formalin for six weeks. The microscopic quality of the sections was excellent with good presentation of brain tissue and equalled that of conventionally processed slides.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.41.5.590