Uncommon Metastasis of a Large-Cell Neuroendocrine Carcinoma From the Lungs to the Buccal Palatal Region

• Published in: Curēus (Palo Alto, CA) CA), 2024-08, Vol.16 (8), p.e67469
• Main Authors: Derfoufi, Jihane, Rezzoug, Fatima, El Jarroudi, Meryem, Nassira, Karich, Al Jarroudi, Ouissam, Brahmi, Sami Aziz, Afqir, Said
• Format: Article
• Language: English
• Subjects: Chemotherapy; Dysphagia; Females; Illnesses; Lung cancer; Lymphatic system; Males; Medical prognosis; Metastasis; Neuroendocrine tumors; Oncology; Pathology; Patients; Smoking; Tomography
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.67469

The metastasis of a primary lung tumor to the mouth cavity is a rare occurrence. In addition, the occurrence of neuroendocrine bronchial carcinoma with large cells is uncommon. When metastases are not possible to surgically remove, the conventional treatment for large-cell neuroendocrine tumors (LCNET) is still used. The etiology of these metastases remains inadequately comprehended, rendering their administration very intricate. The oncologist at this institution must possess a comprehensive comprehension of how to effectively oversee the patient's quality of life to guarantee the uninterrupted progression of therapy. This paper is a case study of a 51-year-old male patient who was hospitalized due to a severe dry cough and dysphonia that began two months prior to seeking medical consultation. Gingival hyperplasia was diagnosed during a clinical examination. The diagnosis of LCNET (carcinoma of the lung) was determined after a thorough etiological investigation utilizing gingival samples and pulmonary tissue. The objective of this study was to provide a description of our case, conduct an analysis of the response to therapy, and make a contribution to the current body of research. The purpose was to encourage more investigation into this type of metastasis, aiming to get a deeper comprehension of the mechanisms behind the metastatic spread and assess its predictive significance in future instances.