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Remember oligodendrocytes: Uncovering their overlooked role in Alzheimer's disease

Our understanding of Alzheimer's disease (AD) has evolved from focusing solely on neurons to recognizing the role of glia. A recent study in PLOS Biology revealed that oligodendrocytes are an important source of Aβ that impairs neuronal function.

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Bibliographic Details
Published in:PLoS biology 2024-09, Vol.22 (9), p.e3002798
Main Authors: Spieth, Lena, Simons, Mikael
Format: Article
Language:English
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Description
Summary:Our understanding of Alzheimer's disease (AD) has evolved from focusing solely on neurons to recognizing the role of glia. A recent study in PLOS Biology revealed that oligodendrocytes are an important source of Aβ that impairs neuronal function.
ISSN:1545-7885
1544-9173
1545-7885
DOI:10.1371/journal.pbio.3002798