The Clinical Profile of Patients With Acute Decompensated Heart Failure Presenting to the Emergency Department at a Tertiary Care Hospital in India

• Published in: Curēus (Palo Alto, CA) CA), 2024-08, Vol.16 (8), p.e67773
• Main Authors: Shinde, Varsha, Thakkar, Dhruvkumar, Mavudelli, Sharmila J
• Format: Article
• Language: English
• Subjects: Age; Anemia; Asthma; Cardiac arrhythmia; Cardiology; Cardiovascular disease; Chronic illnesses; Chronic obstructive pulmonary disease; Coronary vessels; Demographics; Diabetes; Dyspnea; Edema; Ejection fraction; Emergency medical care; Emergency Medicine; Epidemiology; Heart attacks; Heart failure; Hospitals; Hypertension; Hypothesis testing; Internal Medicine; Ischemia; Risk factors; Software; Statistical analysis; Vital signs
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.67773

Background Acute decompensated heart failure (ADHF) poses a significant burden on healthcare systems globally, including in India, due to its high morbidity and mortality rates. This study aimed to evaluate the clinical characteristics of patients presenting with ADHF to the emergency department (ED) of a tertiary care hospital in India. Methodology This observational study was conducted at Dr. D. Y. Patil Medical College, Hospital, and Research Centre in Pune, India. Ninety patients aged 12 years and older who presented with signs and symptoms of heart failure (HF) to the ED between January 2023 and March 2024 were enrolled as participants. Ethical approval was obtained. Written consent was obtained from all participants. Clinical diagnoses were based on patient history, physical examination, chest radiograph, point-of-care ultrasound (POCUS), electrocardiography (ECG), echocardiography, and radiological and laboratory findings. Data were analyzed using IBM SPSS Statistics version 29.0.2.0 (Armonk, NY: IBM Corp.) and represented as mean±SD, frequency (n), and percentage. Results The study involved 90 participants with a mean age of 61.1±16.3 years. The cohort comprised 51 males (56.7%) and females 39 (43.3%). Dyspnea was the most common clinical presentation in all participants, followed by swelling of feet in 58 (64.4%) cases. The mean systolic blood pressure noted was 142.1±42.8 mmHg. Hypertension was the most frequently identified risk factor, present in 52 (57.8%) cases. The most common precipitating factor identified was anemia in 39 (43.3%) cases. Point-of-care ultrasonography (pulmonary) revealed significant B-lines (≥2 of the eight thoracic zones with ≥3 B-lines or B-line count in all eight zones ≥10) in 85 (94.4%) cases. B-type natriuretic peptide (BNP) was elevated in all participants. The mean hemoglobin levels in males and females were 13.2±2.6 g/dL and 10.6±2.8 g/dL, respectively. The mean serum sodium level was 132.4±6.2 mEq/dL. Serum sodium level below 135.0 mEq/L (hyponatremia) was found in 53 (58.9%) cases. The mean serum creatinine level was 1.7±1.4 mg/dL. Diuretics were the most common treatment modality used in the ED. More than half of the patients (72.2%) were transferred to the intensive care unit; the mortality rate in the ED was 2.2%. Conclusion This study provides comprehensive insights into the characteristics, management, and outcomes of ADHF patients presenting to the ED of a tertiary care hospital in India. The findings highl