Multidimensional Analysis of Quality of Life in Patients with Chronic Non-Cancer Pain and Short- and Long-Term Intrathecal Analgesic Therapy

Intrathecal drug delivery (IDD) is part of the fourth analgesic step. Evidence on the quality of life of patients with refractory chronic non-cancer pain (CNCP) using these devices and their long-term outcomes is scarce. This study aims to evaluate patients with IDD to assess their HRQoL. Additional...

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Published in:Healthcare (Basel) 2024-09, Vol.12 (18), p.1870
Main Authors: Sánchez-García, Manuel Alejandro, Alcázar-Navarrete, Bernardino, Cortiñas-Saenz, Manuel, Cordero Tous, Nicolás, Gálvez Mateos, Rafael
Format: Article
Language:English
Subjects:
Analgesics
Back pain
Cancer therapies
Care and treatment
Chronic pain
Consent
Dosage and administration
Drug delivery systems
Health aspects
Injections, Spinal
Morphine
Narcotics
Patient outcomes
Patient satisfaction
Population
Quality of life
Questionnaires
Self report
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container_issue 18
container_start_page 1870
container_title Healthcare (Basel)
container_volume 12
creator Sánchez-García, Manuel Alejandro
Alcázar-Navarrete, Bernardino
Cortiñas-Saenz, Manuel
Cordero Tous, Nicolás
Gálvez Mateos, Rafael
description Intrathecal drug delivery (IDD) is part of the fourth analgesic step. Evidence on the quality of life of patients with refractory chronic non-cancer pain (CNCP) using these devices and their long-term outcomes is scarce. This study aims to evaluate patients with IDD to assess their HRQoL. Additionally, the study seeks to understand the patients' satisfaction with the treatment and changes in pain magnitude over time. Adult patients with CNCP and intrathecal drug delivery systems (IDDS) were included. The study population was divided into two groups: less than and more than 15 years of treatment. HRQoL was analyzed using validated questionnaires. Pain reduction was assessed using the visual analog scale (VAS), and treatment satisfaction was evaluated using the Patient Global Impression of Improvement scale. The results indicate a poor HRQoL in IDD patients, with better scores in the group with ≥15 years of treatment. Pain reduction was similar in both groups, and patients reported a positive satisfaction level with the treatment. HRQoL in CNCP patients is severely affected. Long-term IDD patients have a similar or even better HRQoL in some respects compared to those with shorter follow-ups. IDD patients experienced pain reduction, with most feeling better or much better.
doi_str_mv 10.3390/healthcare12181870
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subjects Analgesics
Back pain
Cancer therapies
Care and treatment
Chronic pain
Consent
Dosage and administration
Drug delivery systems
Health aspects
Injections, Spinal
Morphine
Narcotics
Patient outcomes
Patient satisfaction
Population
Quality of life
Questionnaires
Self report
title Multidimensional Analysis of Quality of Life in Patients with Chronic Non-Cancer Pain and Short- and Long-Term Intrathecal Analgesic Therapy
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