Association between Estrogen Levels and Temporomandibular Disorders: An Updated Systematic Review

The aim of this systematic review is to evaluate the impact of estrogen levels on the occurrence of temporomandibular disorders (TMDs) in humans. Searches were conducted in the same databases as follows: PubMed, the Cochrane Collaboration database, and the Scopus database. In accordance with the MeS...

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Bibliographic Details
Published in:International journal of molecular sciences 2024-09, Vol.25 (18), p.9867
Main Authors: Zieliński, Grzegorz, Pająk-Zielińska, Beata
Format: Article
Language:English
Subjects:
Cartilage
Estrogens
Estrogens - blood
Estrogens - metabolism
Hormone replacement therapy
Humans
Menstruation
Osteoarthritis
Ovulation
Pain
Questionnaires
Review
Systematic review
Temporomandibular Joint - metabolism
Temporomandibular Joint - pathology
Temporomandibular joint disorders
Temporomandibular Joint Disorders - blood
Temporomandibular Joint Disorders - etiology
Temporomandibular Joint Disorders - metabolism
Womens health
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Description
Summary:The aim of this systematic review is to evaluate the impact of estrogen levels on the occurrence of temporomandibular disorders (TMDs) in humans. Searches were conducted in the same databases as follows: PubMed, the Cochrane Collaboration database, and the Scopus database. In accordance with the MeSH database and previous work, the following keywords were used: 'estrogens' and 'temporomandibular joint disorders'. Twelve studies were included in the review and were assessed for the quality of evidence. Estrogen levels are associated with pain modulation in the temporomandibular joint and the entire orofacial region. There is insufficient evidence to either confirm or refute the influence of estrogen on the occurrence of TMDs. The study was registered under the identifier: 10.17605/OSF.IO/BC7QF.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms25189867