Prognostic Value of Transthoracic Impedance Cardiography, Amino-Terminal Pro-B-Type Natriuretic Peptide Levels, The Six-Minute Walk Test, and Chest X-Ray in Elderly Patients with Chronic Heart Failure: A Comparative Study in Lithuania

BACKGROUND Chronic heart failure (CHF) is a complex clinical syndrome associated with frequent, recurrent, and long-term hospitalizations. This study from a single center in Lithuania aimed to evaluate outcomes in 87 elderly patients hospitalized with CHF. The methods used included comparing transth...

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Published in:Medical science monitor 2024-09, Vol.30, p.e945647
Main Authors: Ališauskas, Andrius, Dzikevičiūtė, Kornelija, Rimšaitė, Urtė, Naudžiūnas, Albinas, Razvadauskas, Haroldas, Zinkienė, Diana, Repečka, Tomas, Jucevičius, Jonas, Sadauskas, Saulius
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cardiography, Impedance - methods
Chronic Disease
Clinical Research
Female
Heart Failure - blood
Heart Failure - physiopathology
Humans
Lithuania
Male
Middle Aged
Natriuretic Peptide, Brain - blood
Peptide Fragments - blood
Prognosis
Proportional Hazards Models
Radiography, Thoracic - methods
Walk Test - methods
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Summary:BACKGROUND Chronic heart failure (CHF) is a complex clinical syndrome associated with frequent, recurrent, and long-term hospitalizations. This study from a single center in Lithuania aimed to evaluate outcomes in 87 elderly patients hospitalized with CHF. The methods used included comparing transthoracic impedance cardiography (ICG), amino-terminal pro-B-type natriuretic peptide (NT-proBNP) levels, the six-minute walk test (6MWT), and dilatation of the right pulmonary artery on chest X-ray (dRPAcXR). MATERIAL AND METHODS The study sample consisted of 87 patients (49 men and 38 women). All subjects underwent 6MWT and ICG in addition to the standard CHF tests. The median duration of the follow-up was 23 months. Data about patient outcomes were gathered from the National Medical Record Database. RESULTS By multivariate Cox proportional analysis, thoracic fluid content (TFC) ≥41.1 1/kΩ (hazard ratio [HR] 32.354, 95% confidence interval [CI] 2.758-379.488), NT-proBNP ≥332.0 pmol/L (HR 4.739, 95% CI 1.656-13.559), 6-minute walk distance (6MWD) ≤203.5 m (HR 3.975, 95% CI 1.002-15.770), and dRPAcXR (HR 5.555, 95% CI 1.714-18.005) were associated with a poor prognosis in CHF patients (all P
ISSN:1643-3750
1234-1010
1643-3750
DOI:10.12659/MSM.945647