gamma-Glutamyl transferase isoenzymes in human bile

The gamma-glutamyl transferase isoenzymes of bile were studied using electrophoretic, gel filtration, and ultracentrifugation techniques. In view of the known association of other biliary enzymes with lipids the effects of butanol extraction were investigated. The results show the presence of four i...

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Published in:Journal of clinical pathology 1978-07, Vol.31 (7), p.666-670
Main Authors: Wenham, P R, Price, C P, Sammons, H G
Format: Article
Language:English
Subjects:
Bile - enzymology
Butanols
Chromatography, Gel
gamma-Glutamyltransferase - metabolism
Humans
Isoenzymes - metabolism
Ultracentrifugation
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Price, C P
Sammons, H G
description The gamma-glutamyl transferase isoenzymes of bile were studied using electrophoretic, gel filtration, and ultracentrifugation techniques. In view of the known association of other biliary enzymes with lipids the effects of butanol extraction were investigated. The results show the presence of four isoenzymes of gamma-glutamyl transferase in bile, differing in electrophoretic mobilities, molecular size, and density. The correlation between the properties of biliary gamma-glutamyl transferase and of alkaline phosphatase is discussed.
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subjects Bile - enzymology
Butanols
Chromatography, Gel
gamma-Glutamyltransferase - metabolism
Humans
Isoenzymes - metabolism
Ultracentrifugation
title gamma-Glutamyl transferase isoenzymes in human bile
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