An evaluation of the ToxHA test for the detection of antibodies to Toxoplasma gondii in human serum

The titre of antibodies to Toxoplasma gondii was compared in 1985 sera by use of an indirect haemagglutination test (ToxHA test--Wellcome Reagents Ltd) and the dye test. Sera from 42 patients with clinical or serological indications of recent toxoplasmosis were also examined to determine if the ToxH...

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Bibliographic Details
Published in:Journal of clinical pathology 1980-07, Vol.33 (7), p.644-647
Main Authors: Balfour, A H, Bridges, J B, Harford, J P
Format: Article
Language:English
Subjects:
Antibodies - analysis
Evaluation Studies as Topic
Hemagglutination Tests - methods
Humans
Methylene Blue
Toxoplasma - immunology
Toxoplasmosis - diagnosis
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Summary:The titre of antibodies to Toxoplasma gondii was compared in 1985 sera by use of an indirect haemagglutination test (ToxHA test--Wellcome Reagents Ltd) and the dye test. Sera from 42 patients with clinical or serological indications of recent toxoplasmosis were also examined to determine if the ToxHA test would be of value in detecting early stages of the disease. Nine recent cases of lymphadenopathy and four cases of eye infection were not detected by the test. In addition, a large number of sera found negative in the dye test gave a positive result in the haemagglutination test.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.33.7.644