William Coley: The Pioneer and the Father of Immunotherapy

William Coley was an unacclaimed hero of early cancer treatment. His work is often overshadowed by more recent advancements in immunotherapy. Coley's innovative work in the 1910s and 1930s laid the groundwork for what would become a major field in oncology. His experiments with bacterial vaccin...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-09, Vol.16 (9), p.e69113
Main Authors: Munir, Mishaal, Cheema, Asfand Yar, Ogedegbe, Oboseh J, Aslam, Muhammad Faisal, Kim, San
Format: Article
Language:English
Subjects:
Hematology
Internal Medicine
Oncology
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Summary:William Coley was an unacclaimed hero of early cancer treatment. His work is often overshadowed by more recent advancements in immunotherapy. Coley's innovative work in the 1910s and 1930s laid the groundwork for what would become a major field in oncology. His experiments with bacterial vaccines by making use of the immune system to combat cancer preceded contemporary immunotherapy for several decades. This review provides a comprehensive exploration of Coley's life, his groundbreaking research, the socio-scientific challenges he faced, and his lasting impact on cancer treatment. Even though he faced lots of initial resistance and challenges, Coley's work has influenced modern immunotherapy practices.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.69113