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Outpatient parenteral antimicrobial therapy (OPAT) using a continuous ambulatory delivery device (CADD) allowing treatment with multiple daily doses: a brief report of a Norwegian experience
Abstract Background Outpatient parenteral antimicrobial therapy (OPAT) is safe, effective and increasingly available. While OPAT in Norwegian healthcare has been rare, a new continuous ambulatory delivery device (CADD) allowing multiple daily dosing treatments has been innovated making OPAT more acc...
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Published in: | JAC-antimicrobial resistance 2024-10, Vol.6 (5), p.dlae155 |
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creator | Skogen, Vegard Helleren, Rita Jacobsen, Marianne Giske Opsal, Anne Gallefoss, Frode |
description | Abstract
Background
Outpatient parenteral antimicrobial therapy (OPAT) is safe, effective and increasingly available. While OPAT in Norwegian healthcare has been rare, a new continuous ambulatory delivery device (CADD) allowing multiple daily dosing treatments has been innovated making OPAT more accessible.
Objectives
To describe the clinical outcome and safety using CADD in an OPAT setting.
Methods
Adult patients in need of parenteral antibiotic treatment were offered OPAT and discharged with a programmable digital infusion pump allowing multiple daily dosings.
Results
Altogether, 170 patients were included in the study, among which 21% of all patients (36 of 170) were readmitted to hospital while receiving OPAT or within 30 days after end of intravenous antibiotics. None of the 170 patients died due to OPAT and allergies were not noticeable as a problem.
Conclusions
We have developed a safe and clinically effective programme offering OPAT in accordance with Norwegian antibiotic treatment guidelines. |
doi_str_mv | 10.1093/jacamr/dlae155 |
format | article |
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Background
Outpatient parenteral antimicrobial therapy (OPAT) is safe, effective and increasingly available. While OPAT in Norwegian healthcare has been rare, a new continuous ambulatory delivery device (CADD) allowing multiple daily dosing treatments has been innovated making OPAT more accessible.
Objectives
To describe the clinical outcome and safety using CADD in an OPAT setting.
Methods
Adult patients in need of parenteral antibiotic treatment were offered OPAT and discharged with a programmable digital infusion pump allowing multiple daily dosings.
Results
Altogether, 170 patients were included in the study, among which 21% of all patients (36 of 170) were readmitted to hospital while receiving OPAT or within 30 days after end of intravenous antibiotics. None of the 170 patients died due to OPAT and allergies were not noticeable as a problem.
Conclusions
We have developed a safe and clinically effective programme offering OPAT in accordance with Norwegian antibiotic treatment guidelines.</description><identifier>ISSN: 2632-1823</identifier><identifier>EISSN: 2632-1823</identifier><identifier>DOI: 10.1093/jacamr/dlae155</identifier><identifier>PMID: 39403675</identifier><language>eng</language><publisher>UK: Oxford University Press</publisher><subject>Original</subject><ispartof>JAC-antimicrobial resistance, 2024-10, Vol.6 (5), p.dlae155</ispartof><rights>The Author(s) 2024. Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy. 2024</rights><rights>The Author(s) 2024. Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy.</rights><rights>info:eu-repo/semantics/openAccess</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c334t-983869bf77ad818253575852632eba906793d41d150e83915812dd2bf60af0a53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472154/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472154/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,1598,26544,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39403675$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Skogen, Vegard</creatorcontrib><creatorcontrib>Helleren, Rita</creatorcontrib><creatorcontrib>Jacobsen, Marianne Giske</creatorcontrib><creatorcontrib>Opsal, Anne</creatorcontrib><creatorcontrib>Gallefoss, Frode</creatorcontrib><title>Outpatient parenteral antimicrobial therapy (OPAT) using a continuous ambulatory delivery device (CADD) allowing treatment with multiple daily doses: a brief report of a Norwegian experience</title><title>JAC-antimicrobial resistance</title><addtitle>JAC Antimicrob Resist</addtitle><description>Abstract
Background
Outpatient parenteral antimicrobial therapy (OPAT) is safe, effective and increasingly available. While OPAT in Norwegian healthcare has been rare, a new continuous ambulatory delivery device (CADD) allowing multiple daily dosing treatments has been innovated making OPAT more accessible.
Objectives
To describe the clinical outcome and safety using CADD in an OPAT setting.
Methods
Adult patients in need of parenteral antibiotic treatment were offered OPAT and discharged with a programmable digital infusion pump allowing multiple daily dosings.
Results
Altogether, 170 patients were included in the study, among which 21% of all patients (36 of 170) were readmitted to hospital while receiving OPAT or within 30 days after end of intravenous antibiotics. None of the 170 patients died due to OPAT and allergies were not noticeable as a problem.
Conclusions
We have developed a safe and clinically effective programme offering OPAT in accordance with Norwegian antibiotic treatment guidelines.</description><subject>Original</subject><issn>2632-1823</issn><issn>2632-1823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>TOX</sourceid><sourceid>3HK</sourceid><recordid>eNqFUj1v2zAQFYoWTZBm7dhytAcnpCiKUpfCcPoFBHWHdCZO0slmQIkqSdnxn-tvK1U7QTp1uq937w4PL0neMnrFaMmv76GGzl03BpAJ8SI5T3OeLliR8pfP8rPk0vt7SmkqqMxk-jo542VGeS7FefJ7PYYBgsY-kAFcDOjAEOiD7nTtbKVjFbaxORzIbP1jeTcno9f9hgCpbUT1ox09ga4aDQTrDqRBo3f4N9npGslstby5mRMwxu6nveAQQjfd2-uwJd1ogh4Mkga0iUvWo_8QySunsSUOB-sCsW3sfLdujxsNPcGHAeO4r_FN8qoF4_HyFC-Sn58_3a2-Lm7XX76tlreLmvMsLMqCF3lZtVJCU0RNBBdSFGKSCCsoaS5L3mSsYYJiwUsmCpY2TVq1OYWWguAXyccj7zBWHTZ1fD_KpAanO3AHZUGrfye93qqN3SnGouJMZJHh_ZGhdtpH2VRvHShGKZeKi1wUETE73XD214g-qE77Go2BHqPGijOW5zKX2UR29UhmvXfYPn3CqJqsoY7WUCdrxIV3z_9_gj8aIQLmR4Adh_-R_QFrdMen</recordid><startdate>20241014</startdate><enddate>20241014</enddate><creator>Skogen, Vegard</creator><creator>Helleren, Rita</creator><creator>Jacobsen, Marianne Giske</creator><creator>Opsal, Anne</creator><creator>Gallefoss, Frode</creator><general>Oxford University Press</general><scope>TOX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>3HK</scope><scope>5PM</scope></search><sort><creationdate>20241014</creationdate><title>Outpatient parenteral antimicrobial therapy (OPAT) using a continuous ambulatory delivery device (CADD) allowing treatment with multiple daily doses: a brief report of a Norwegian experience</title><author>Skogen, Vegard ; Helleren, Rita ; Jacobsen, Marianne Giske ; Opsal, Anne ; Gallefoss, Frode</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c334t-983869bf77ad818253575852632eba906793d41d150e83915812dd2bf60af0a53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Original</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Skogen, Vegard</creatorcontrib><creatorcontrib>Helleren, Rita</creatorcontrib><creatorcontrib>Jacobsen, Marianne Giske</creatorcontrib><creatorcontrib>Opsal, Anne</creatorcontrib><creatorcontrib>Gallefoss, Frode</creatorcontrib><collection>Oxford University Press Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>NORA - Norwegian Open Research Archives</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>JAC-antimicrobial resistance</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Skogen, Vegard</au><au>Helleren, Rita</au><au>Jacobsen, Marianne Giske</au><au>Opsal, Anne</au><au>Gallefoss, Frode</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outpatient parenteral antimicrobial therapy (OPAT) using a continuous ambulatory delivery device (CADD) allowing treatment with multiple daily doses: a brief report of a Norwegian experience</atitle><jtitle>JAC-antimicrobial resistance</jtitle><addtitle>JAC Antimicrob Resist</addtitle><date>2024-10-14</date><risdate>2024</risdate><volume>6</volume><issue>5</issue><spage>dlae155</spage><pages>dlae155-</pages><issn>2632-1823</issn><eissn>2632-1823</eissn><abstract>Abstract
Background
Outpatient parenteral antimicrobial therapy (OPAT) is safe, effective and increasingly available. While OPAT in Norwegian healthcare has been rare, a new continuous ambulatory delivery device (CADD) allowing multiple daily dosing treatments has been innovated making OPAT more accessible.
Objectives
To describe the clinical outcome and safety using CADD in an OPAT setting.
Methods
Adult patients in need of parenteral antibiotic treatment were offered OPAT and discharged with a programmable digital infusion pump allowing multiple daily dosings.
Results
Altogether, 170 patients were included in the study, among which 21% of all patients (36 of 170) were readmitted to hospital while receiving OPAT or within 30 days after end of intravenous antibiotics. None of the 170 patients died due to OPAT and allergies were not noticeable as a problem.
Conclusions
We have developed a safe and clinically effective programme offering OPAT in accordance with Norwegian antibiotic treatment guidelines.</abstract><cop>UK</cop><pub>Oxford University Press</pub><pmid>39403675</pmid><doi>10.1093/jacamr/dlae155</doi><oa>free_for_read</oa></addata></record> |
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source | Open Access: PubMed Central; NORA - Norwegian Open Research Archives; Oxford University Press Open Access |
subjects | Original |
title | Outpatient parenteral antimicrobial therapy (OPAT) using a continuous ambulatory delivery device (CADD) allowing treatment with multiple daily doses: a brief report of a Norwegian experience |
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