Retrospective Cohort Study Demonstrates Tolerance and Adherence to Pea-Based Complete Enteral Formula When Transitioned from a Previous Hypoallergenic Product

Plant-based formulas have become increasingly popular due to their health benefits, environmental concerns, cultural beliefs, improved palatability, and decreased cost. A retrospective chart review of medically stable children transitioning from a hypoallergenic formula to a yellow pea protein plant...

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Bibliographic Details
Published in:Nutrients 2024-10, Vol.16 (19), p.3365
Main Authors: Withrow, Nicole A, Al-Tawil, Youhanna, Patterson, P J, Wilson, Madden, Ryan, Erika, Millovich, Vanessa, Valentine, Christina J
Format: Article
Language:English
Subjects:
Abdomen
Adolescent
Allergens
Amino acids
Child
Child, Preschool
Constipation
Diarrhea
Diet therapy
Electronic health records
Female
Food allergies
Food Hypersensitivity
Health aspects
Humans
Infant
Infant Formula
Infant formulas
Male
Medical records
Milk
Milk allergy
Nausea
Nutritional aspects
Patient Compliance
Patients
Peas
Pediatric research
Pediatrics
Phytochemicals
Pisum sativum
Plant-based foods
Proteins
Retrospective Studies
Rice
Vomiting
Weight Gain
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Summary:Plant-based formulas have become increasingly popular due to their health benefits, environmental concerns, cultural beliefs, improved palatability, and decreased cost. A retrospective chart review of medically stable children transitioning from a hypoallergenic formula to a yellow pea protein plant-based formula (PPPBF) was included. This study aimed to assess gastrointestinal tolerance, weight changes, and adherence to receiving a unique PPPBF. Healthcare providers (HCPs) from pediatric clinics across the United States who requested increased PPPBF samples between the dates of 1 November 2021and 31 January 2022 and again from 1 February 2022 to 15 April 2022 inputted survey data. The HCPs selected participants based on the inclusion criteria. Seventy-three completed patient surveys were included of children (ages 1-18 years old, 41% females, 59% males). After the transition to PPPBF, 38.4% experienced improvement in GI tolerance, 56.2% experienced no change, and 5.5% reported worsening GI tolerance. There was a 95% adherence rate, and 98.9% reported no adverse reactions or allergic manifestations after formula transition. Transitioning from a hypoallergenic formula to a PPPBF showed a trend toward stable GI tolerance, weight gain or stability, and adherence. A PPPBF offers a first-choice option for children who are on hypoallergenic formulas due to intolerance.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu16193365