IgA Vasculitis Associated With Levofloxacin Use in an Adult Female: A Case Report

• Published in: Curēus (Palo Alto, CA) CA), 2024-10, Vol.16 (10), p.e71567
• Main Authors: Gómez Contreras, Karen A, Alonzo Canul, María E, Mena Rodríguez, Ana L, Castillo Baas, Melissa G, Vargas Gutiérrez, David A
• Format: Article
• Language: English
• Subjects: Dermatology; Rheumatology
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.71567

Immunoglobulin A (IgA) vasculitis, once known as Henoch-Schönlein purpura in recognition of the physicians who first identified it, is an acute form of vasculitis, associated with a deposition of immune complexes, self-limited that affects small-caliber vessels. It usually occurs in children and rarely in adults. This disease can be induced by multiple factors such as exposure to certain infectious antigens such as viruses or bacteria, drugs, and toxins, and even genetic predisposition has been described. Although the use of some antibiotics is known as a risk factor for the development of IgA vasculitis, it may not be considered when approaching and treating an adult with a related clinical condition, since its frequency is rare. We present the case of a 26-year-old woman with a history of an upper respiratory tract infection who required treatment with levofloxacin and subsequently developed palpable purpura.