Performance of the Systemic Lupus Erythematosus Risk Probability Index (SLERPI) in a cohort of Colombian population

Objective To evaluate the performance of the Systemic Lupus Erythematosus Risk Probability Index (SLERPI) in Colombian patients with systemic lupus erythematosus (SLE). Methods The Colombian cohort included 435 SLE patients and 430 controls with other autoimmune diseases (ADs). Clinical and serologi...

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Published in:Clinical rheumatology 2024-11, Vol.43 (11), p.3313-3322
Main Authors: Celis-Andrade, Mariana, Rojas, Manuel, Rodríguez, Yhojan, Calderon, Juan Benjamín, Rodríguez-Jiménez, Mónica, Monsalve, Diana M., Acosta-Ampudia, Yeny, Ramírez-Santana, Carolina
Format: Article
Language:English
Subjects:
Autoimmune diseases
Cutaneous Lupus Erythematosus
Discoid lupus erythematosus
Exanthema
Hematology
Immunology
Lung diseases
Lupus
Lupus nephritis
Medicine
Medicine & Public Health
Neurological complications
Original
Original Article
Performance evaluation
Rheumatology
Systemic lupus erythematosus
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Summary:Objective To evaluate the performance of the Systemic Lupus Erythematosus Risk Probability Index (SLERPI) in Colombian patients with systemic lupus erythematosus (SLE). Methods The Colombian cohort included 435 SLE patients and 430 controls with other autoimmune diseases (ADs). Clinical and serological data were collected, and SLE was indicated by SLERPI scores > 7. The American College of Rheumatology (ACR)-1997, Systemic Lupus International Collaborating Clinics (SLICC)-2012, and European League Against Rheumatism (EULAR)/ACR-2019 criteria were used as reference standards. The impact of overt polyautoimmunity (PolyA) on SLERPI performance was assessed. Additionally, multivariate lineal regression analysis was performed to evaluate the contribution of SLERPI features to the overall SLERPI score. Results SLE patients had higher SLERPI scores (P 
ISSN:0770-3198
1434-9949
1434-9949
DOI:10.1007/s10067-024-07108-x