Association Between Body Mass Index Changes and All-Cause Mortality in Parkinson’s Disease

Background: Whether body weight changes are associated with Parkinson’s disease (PD) mortality remains uncertain. Objective: To investigate the association between changes in body mass index (BMI) and all-cause mortality in patients with PD. Methods: This nationwide cohort study enrolled 20,703 indi...

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Bibliographic Details
Published in:Journal of Parkinson's disease 2024-01, Vol.14 (7), p.1441-1450
Main Authors: Yoon, Seo Yeon, Choi, Ja Young, Nam, Ga Eun, Jung, Jin-Hyung, Han, Kyungdo, Kang, Sung Hoon, Kim, Chi Kyung, Kim, Yong Wook, Koh, Seong-Beom
Format: Article
Language:English
Subjects:
Body mass index
Body weight
Body weight gain
Body weight loss
Diagnosis
Mortality
Movement disorders
Neurodegenerative diseases
Obesity
Overweight
Parkinson's disease
Research Report
Underweight
Weight control
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Summary:Background: Whether body weight changes are associated with Parkinson’s disease (PD) mortality remains uncertain. Objective: To investigate the association between changes in body mass index (BMI) and all-cause mortality in patients with PD. Methods: This nationwide cohort study enrolled 20,703 individuals with new-onset PD (ICD-10 code: G20 and a rare intractable disease registration code: V124) who underwent health screening program by the Korean National Health Insurance Service within two years from pre- and post-PD diagnosis. We identified nine BMI change groups based on three BMI status: underweight (BMI 
ISSN:1877-7171
1877-718X
DOI:10.3233/JPD-240181