A Case of Hypercalcaemia With Suppressed Parathyroid Hormone in a Middle-Aged Female: Diagnostic Challenge and Association With Hyperthyroidism

Hypercalcaemia with suppressed parathyroid hormone (PTH) typically raises concern for malignancy-related, granulomatous disorder-related or drug-related hypercalcaemia but can occasionally be caused by less common conditions. We present the case of a middle-aged female with hypercalcaemia with reduc...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-10, Vol.16 (10), p.e72020
Main Authors: Chengalpet Jaishankar, Bharathiraman, Kibria, Saifuddin Mohammad, Sudarshanan, Aditya, Patlolla, Niharika, Fernandez James, Cornelius
Format: Article
Language:English
Subjects:
Endocrinology/Diabetes/Metabolism
Internal Medicine
Oncology
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Summary:Hypercalcaemia with suppressed parathyroid hormone (PTH) typically raises concern for malignancy-related, granulomatous disorder-related or drug-related hypercalcaemia but can occasionally be caused by less common conditions. We present the case of a middle-aged female with hypercalcaemia with reduced PTH levels despite vitamin insufficiency, who was eventually diagnosed with autoimmune hyperthyroidism. The diagnostic challenge arose from the atypical association of hyperthyroidism and hypercalcaemia. This case highlights the importance of considering hyperthyroidism in the differential diagnosis of hypercalcaemia.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.72020