Dynapenic abdominal obesity and activities of daily living disability among older adults residing in low- and middle-income countries

• Published in: Aging clinical and experimental research 2024-10, Vol.36 (1), p.212, Article 212
• Main Authors: Smith, Lee, López Sánchez, Guillermo F., Soysal, Pinar, Kostev, Karel, Jacob, Louis, Veronese, Nicola, Tully, Mark A., Butler, Laurie, Barnett, Yvonne, Pizzol, Damiano, Shin, Jae Il, Koyanagi, Ai
• Format: Article
• Language: English
• Subjects: Abdomen; Activities of Daily Living; Aged; Aged, 80 and over; Cross-Sectional Studies; Developing Countries; Diabetes; Disabled Persons - statistics & numerical data; Female; Geriatrics/Gerontology; Hand Strength - physiology; Humans; Hypertension; Low income groups; Male; Medicine; Medicine & Public Health; Middle Aged; Obesity; Obesity, Abdominal - epidemiology; Older people; Waist Circumference
• ISSN: 1720-8319; 1594-0667; 1720-8319
• DOI: 10.1007/s40520-024-02864-x

Background Dynapenic abdominal obesity (DAO) may be associated with an increased risk of disability. However, to date, this has not been investigated in low- and middle-income countries (LMICs), while the mediators are largely unknown. Aims Therefore, we aimed to investigate the association between DAO and activities of daily living (ADL) disability, and to identify potential mediators among older adults from six LMICs. Methods Cross-sectional, nationally representative data from the WHO Study on global AGEing and adult health were analyzed. Data on 20,198 adults aged ≥ 60 years were analyzed [mean (SD) age 69.3 (13.1) years; 54.1% females]. Dynapenia was defined as handgrip strength of  102 cm for men. DAO was defined as having both dynapenia and abdominal obesity. Disability was defined as severe or extreme difficulty in conducting at least one of six types of ADL. Multivariable logistic regression and mediation analysis were conducted. Results Compared to no dynapenia and no abdominal obesity, DAO was significantly associated with 2.08 (95%CI = 1.37–3.17) times higher odds for ADL disability Mediation analysis showed that diabetes (mediated percentage 4.7%), hypertension (7.2%), and angina (7.7%) were significant mediators in the association between DAO and ADL disability. Conclusions DAO was associated with increased odds for ADL disability among older adults from LMICs. Future longitudinal studies are warranted to assess temporal associations, and whether addressing or preventing DAO can impact on future occurrence of disability.