Clinical pain management: Current practice and recent innovations in research

Chronic pain affects one in five adults. It is not only a major cause of disability for individual patients but also a driver of costs for entire healthcare systems. Treatment of pain remains a challenge, and the use of opioids has further led to a concurrent opioid epidemic. In this review, we disc...

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Bibliographic Details
Published in:Cell reports. Medicine 2024-10, Vol.5 (10), p.101786, Article 101786
Main Authors: Wang, Jing, Doan, Lisa V.
Format: Article
Language:English
Subjects:
Analgesics, Opioid - therapeutic use
chronic pain
Chronic Pain - drug therapy
Chronic Pain - therapy
Humans
neuromodulation
neuropathic pain
nociceptive pain
nociplastic pain
opioids
Pain Management - methods
pain treatment
Review
Citations: Items that this one cites
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Summary:Chronic pain affects one in five adults. It is not only a major cause of disability for individual patients but also a driver of costs for entire healthcare systems. Treatment of pain remains a challenge, and the use of opioids has further led to a concurrent opioid epidemic. In this review, we discuss current standard treatment options for chronic pain, including pharmacological, behavioral, and interventional treatments. In addition, we review ongoing research in different areas that will potentially unlock new therapies. [Display omitted] Wang et al. provide a narrative review of current standard treatment options for chronic pain as well as an overview of recent advances in pain therapeutics.
ISSN:2666-3791
2666-3791
DOI:10.1016/j.xcrm.2024.101786