Transcatheter edge-to-edge mitral valve repair for severe heart failure in a young woman with polymyositis: A case report

Polymyositis (PM) and dermatomyositis (DM) are chronic inflammatory muscle disorders characterized by muscle weakness and fatigue. They are histopathologically defined by inflammatory cell infiltrates in the skeletal muscle. In a recent meta-analysis, the incidence of cardiovascular complications in...

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Bibliographic Details
Published in:Journal of cardiology cases 2024-09, Vol.30 (3), p.90-93
Main Authors: Fujii, Masayoshi, Onishi, Tetsuari, Yamamoto, Hiroyuki, Takahashi, Nobuyuki, Takaya, Tomofumi, Kawai, Hiroya
Format: Article
Language:English
Subjects:
Case Report
Polymyositis
Transcatheter edge-to-edge mitral valve repair
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Summary:Polymyositis (PM) and dermatomyositis (DM) are chronic inflammatory muscle disorders characterized by muscle weakness and fatigue. They are histopathologically defined by inflammatory cell infiltrates in the skeletal muscle. In a recent meta-analysis, the incidence of cardiovascular complications in patients with PM/DM ranged from 9 to 72 %, with heart failure being the most commonly reported heart disease. In cases of heart failure accompanied by severe mitral regurgitation that is refractory due to guideline-directed medical therapy, the transcatheter edge-to-edge mitral valve repair (TEER) procedure using the MitraClip (Abbott Vascular, Santa Clara, CA, USA) offers an alternative therapeutic approach. We present a pioneering case report describing the successful application of TEER in a young woman with drug-refractory heart failure due to cardiovascular involvement in PM. •In polymyositis (PM)/ dermatomyositis (DM), the most commonly reported clinical heart disorder is heart failure, with some cases attributed to mitral regurgitation.•Patients suffering from systemic inflammatory diseases such as PM/DM often face high surgical risk, and the MitraClip is an effective treatment modality.
ISSN:1878-5409
1878-5409
DOI:10.1016/j.jccase.2024.06.001