A Multifaceted Exploration of Status Asthmaticus: A Retrospective Analysis in a Romanian Hospital

: Status asthmaticus is a severe, life-threatening asthma exacerbation requiring urgent medical intervention. This study aims to examine its epidemiology in Timis County, Romania, over 11 years. : A retrospective analysis was conducted using hospital records from 2013 to 2023, focusing on demographi...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-11, Vol.13 (21), p.6615
Main Authors: Trusculescu, Adriana Ana, Ancusa, Versavia Maria, Pescaru, Camelia Corina, Wellmann, Norbert, Fira-Mladinescu, Corneluta, Oancea, Cristian Iulian, Fira-Mladinescu, Ovidiu
Format: Article
Language:English
Subjects:
Asthma
Biomarkers
Care and treatment
Cytokines
Data analysis
Demographic aspects
Disease
Distribution
Hospitals
Inflammation
Patients
Python
Software
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Summary:: Status asthmaticus is a severe, life-threatening asthma exacerbation requiring urgent medical intervention. This study aims to examine its epidemiology in Timis County, Romania, over 11 years. : A retrospective analysis was conducted using hospital records from 2013 to 2023, focusing on demographic, geospatial, and temporal distributions. Network analysis of the recorded comorbidities was used to identify phenotypic clusters among patients. : Females and older adults were disproportionately affected. Several triggers and geospatial patterns were identified. Five phenotypic clusters were determined: two in the T2-high endotype, two in T2-low, and a mixed one. : The findings highlight the need for personalized asthma management strategies and public healthcare interventions in Timiș County, addressing specific demographic and geospatial factors. This study also provides a valuable reference for similar regions.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13216615