Intravenous administration of ultrasound contrast to critically ill pediatric patients

Background The off-label use of contrast-enhanced ultrasound has been increasingly used for pediatric patients. Objective The purpose of this retrospective study is to report any observed clinical changes associated with the intravenous (IV) administration of ultrasound contrast to critically ill ne...

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Bibliographic Details
Published in:Pediatric radiology 2024-05, Vol.54 (5), p.820-830
Main Authors: Riggs, Becky J., Martinez-Correa, Santiago, Stern, Joseph, Tierradentro-Garcia, Luis Octavio, Haddad, Sophie, Anupindi, Sudha, Back, Susan J., Darge, Kassa, Hwang, Misun
Format: Article
Language:English
Subjects:
Administration, Intravenous
Adolescent
Adolescents
Child
Child, Preschool
Children
Contrast Media - administration & dosage
Critical Illness
Electronic health records
Electronic medical records
Female
Heart
Hemodynamics
Humans
Imaging
Infant
Infant, Newborn
Infants
Intensive care units
Intravenous administration
Male
Medicine
Medicine & Public Health
Neonates
Neuroradiology
Nitric oxide
Nuclear Medicine
Oncology
Original Article
Oxygenation
Patients
Pediatrics
Radiology
Retrospective Studies
Statistical analysis
Ultrasonic imaging
Ultrasonography - methods
Ultrasound
Vasoactive agents
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Description
Summary:Background The off-label use of contrast-enhanced ultrasound has been increasingly used for pediatric patients. Objective The purpose of this retrospective study is to report any observed clinical changes associated with the intravenous (IV) administration of ultrasound contrast to critically ill neonates, infants, children, and adolescents. Materials and methods All critically ill patients who had 1 or more contrast-enhanced ultrasound scans while being closely monitored in the neonatal, pediatric, or pediatric cardiac intensive care units were identified. Subjective and objective data concerning cardiopulmonary, neurological, and hemodynamic monitoring were extracted from the patient’s electronic medical records. Vital signs and laboratory values before, during, and after administration of ultrasound contrast were obtained. Statistical analyses were performed using JMP Pro, version 15. Results were accepted as statistically significant for P -value
ISSN:1432-1998
0301-0449
1432-1998
DOI:10.1007/s00247-024-05898-5