Single high-sensitivity troponin-I for ruling out acute coronary syndrome: a detection limit approach

The aim of this study was determine the incidence of major adverse cardiac events within 30 and 365-days among patients discharged from emergency departments (EDs), following a single high-sensitivity cardiac troponin I test result below or close to the limits of detection (LoD). Patients ≥20 years...

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Bibliographic Details
Published in:European heart journal open 2024-11, Vol.4 (6), p.oeae094
Main Authors: Hickling, Siobhan, Francis, Chelsea J, Chew, Derek P, Mitra, Biswadev, Hillis, Graham S
Format: Article
Language:English
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Short Report
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Summary:The aim of this study was determine the incidence of major adverse cardiac events within 30 and 365-days among patients discharged from emergency departments (EDs), following a single high-sensitivity cardiac troponin I test result below or close to the limits of detection (LoD). Patients ≥20 years old who presented to four EDs from mid-2014 to end-2015, underwent a single high-sensitivity troponin test and were discharged were included. Data from ED presentations, hospital admissions, mortality records, and pathology laboratories were linked and harmonized. High-sensitivity troponin levels were categorized as below (
ISSN:2752-4191
2752-4191
DOI:10.1093/ehjopen/oeae094