Supraventricular tachycardia diagnosis in asthma patients is associated with adverse health outcomes

Introduction Supraventricular tachycardia (SVT) can occur during treatment of an acute asthma exacerbation. There are, however, no data on the long‐term outcomes of children who are diagnosed with both asthma and SVT. This study aims to analyze the impact of SVT in asthmatic children on mortality an...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric pulmonology 2024-12, Vol.59 (12), p.3410-3418
Main Authors: Markus, Havell, Ceneviva, Gary D., Thomas, Neal J., Krawiec, Conrad
Format: Article
Language:English
Subjects:
Adolescent
Asthma
Asthma - complications
Asthma - diagnosis
Asthma - epidemiology
biostatistics
Cardiac arrest
Cardiac arrhythmia
Child
Child, Preschool
critical care
Electronic health records
Electronic Health Records - statistics & numerical data
Female
Heart Arrest - etiology
Humans
Male
Mortality
Original
pulmonology (general)
Retrospective Studies
Tachycardia, Supraventricular - diagnosis
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction Supraventricular tachycardia (SVT) can occur during treatment of an acute asthma exacerbation. There are, however, no data on the long‐term outcomes of children who are diagnosed with both asthma and SVT. This study aims to analyze the impact of SVT in asthmatic children on mortality and/or cardiac arrest, hypothesizing asthmatic subjects with SVT have increased mortality and/or cardiac arrest compared to asthmatic subject with no‐SVT. Methods This was a retrospective cohort study, utilizing the TriNetX© electronic health record (EHR) database that included asthmatic subjects 2–18 years of age. The study population was divided into two groups (subjects with SVT diagnosis and no‐SVT diagnosis). Data related to demographics, diagnostic, procedural, and medication codes were collected. The primary outcome was any death and/or cardiac arrest in a patient after the first asthma diagnosis date. Results This study included 91,066 asthmatic subjects (244 [0.27%] with SVT and 90,822 [99.73%] with no‐SVT). Multivariable logistic regression analysis demonstrated that after controlling for demographic and clinical features, the odds of all‐cause death and/or cardiac arrest after the first reported asthma exacerbation was significantly higher in asthmatic children with SVT compared to no‐SVT (odds ratio [OR]: 4.30, confidence interval [CI]: 2.50–7.39, p 
ISSN:8755-6863
1099-0496
1099-0496
DOI:10.1002/ppul.27219