Widespread form of Majocchi’s granuloma in a kidney transplant recipient

Kidney transplantation is the encouraged kidney replacement therapy due to providing more prolonged survival with a better quality of life. Unfortunately, kidney transplant recipients are susceptible to infections because of long-term utilization of immunosuppression. Despite dermatophyte infections...

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Bibliographic Details
Published in:CEN case reports 2024-12, Vol.13 (6), p.552-556
Main Authors: Uysal, Cihan, Oguz, Hanife, Cifci, Hasan, Kocyigit, Ismail
Format: Article
Language:English
Subjects:
Adult
Antifungal Agents - therapeutic use
Arthrodermataceae - isolation & purification
Case Report
Granuloma - diagnosis
Granuloma - etiology
Granuloma - microbiology
Humans
Immunocompromised Host
Immunosuppressive Agents - adverse effects
Immunosuppressive Agents - therapeutic use
Kidney Transplantation - adverse effects
Male
Medicine
Medicine & Public Health
Nephrology
Skin - microbiology
Skin - pathology
Terbinafine - therapeutic use
Tinea - diagnosis
Treatment Outcome
Urology
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Summary:Kidney transplantation is the encouraged kidney replacement therapy due to providing more prolonged survival with a better quality of life. Unfortunately, kidney transplant recipients are susceptible to infections because of long-term utilization of immunosuppression. Despite dermatophyte infections are generally not life-threatening, the clinical significance has been recently enhanced by an increasing number of immunocompromised patients. We have presented a rare dermatophytosis course, Majocchi's granuloma, that spreads to all extremities during the early post-transplant period. A young kidney transplant recipient was exposed to intensive immunosuppression therapy due to acute rejection in the early period of post-transplantation. After four months, numerous nodular skin lesions were raised on various body parts. An invasive fungal infection was identified in the skin biopsy. Also, Trichophyton rubrum was isolated in the tissue cultures. Consequently, the patient was diagnosed with Majocchi’s granuloma. An effectual treatment was attained with an oral terbinafine tablet. Majocchi’s granuloma is a distinct form of dermatophytosis characterized by the spreading of infection into the dermis. In this unexpected case, we alerted physicians to opportunistic infections in the kidney transplant recipient.
ISSN:2192-4449
2192-4449
DOI:10.1007/s13730-024-00883-1