Clinical features and progress in diagnosis and treatment of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of the central nervous system. Despite a large number of studies, the current prognosis of ALS is still not ideal. This article briefly describes the clinical features including epidemiology, genetic structure and clinical mani...

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Bibliographic Details
Published in:Annals of medicine (Helsinki) 2024-12, Vol.56 (1), p.2399962
Main Authors: Yuan, Dongxiang, Jiang, Shishi, Xu, Renshi
Format: Article
Language:English
Subjects:
Amyotrophic Lateral Sclerosis - diagnosis
Amyotrophic Lateral Sclerosis - epidemiology
Amyotrophic Lateral Sclerosis - genetics
Amyotrophic Lateral Sclerosis - therapy
Humans
Neurology
Prognosis
Review
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Summary:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of the central nervous system. Despite a large number of studies, the current prognosis of ALS is still not ideal. This article briefly describes the clinical features including epidemiology, genetic structure and clinical manifestations, as well as the progress of new diagnostic criteria and treatment of ALS. Meanwhile, we also discussed further both developments and improvements to enhance understanding and accelerating the introduction of the effective treatments of ALS.
ISSN:1365-2060
0785-3890
1365-2060
DOI:10.1080/07853890.2024.2399962