Desmosines in human urine. Amounts in early development and in Marfan's syndrome

Desmosines from 24 h human urine samples were isolated, characterized and quantified. The desmosines are in peptidyl form (1000--1500 molecular weight), and their amount is decreased by two-thirds between 7 and 25 years of age. Patients with Marfan's syndrome have significantly lower urinary am...

Full description

Saved in:
Bibliographic Details
Published in:Biochemical journal 1981-03, Vol.193 (3), p.915-918
Main Authors: Gunja-Smith, Z, Boucek, R J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Amino Acids - urine
Child
Child, Preschool
Chromatography, Gel
Desmosine - analogs & derivatives
Desmosine - urine
Female
Growth
Humans
Male
Marfan Syndrome - urine
Peptides - urine
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Desmosines from 24 h human urine samples were isolated, characterized and quantified. The desmosines are in peptidyl form (1000--1500 molecular weight), and their amount is decreased by two-thirds between 7 and 25 years of age. Patients with Marfan's syndrome have significantly lower urinary amounts of desmosines than do comparable controls during the early development period.
ISSN:0264-6021
1470-8728
DOI:10.1042/bj1930915