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Effect of integrated medicines management on quality of discharge medication information-a secondary endpoint in a randomized controlled trial
High-quality discharge information is important to promote patient safety when patients are transferred from hospital to primary care. Patients with multiple long-term conditions are especially vulnerable to insufficient transfer of medication information, as they use many medications and have compl...
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Published in: | International journal for quality in health care 2024-12, Vol.36 (4) |
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container_title | International journal for quality in health care |
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description | High-quality discharge information is important to promote patient safety when patients are transferred from hospital to primary care. Patients with multiple long-term conditions are especially vulnerable to insufficient transfer of medication information, as they use many medications and have complex interactions with the healthcare services. The aim of this study was to investigate the effect of integrated medicines management provided to hospitalized multimorbid patients on the quality of the discharge medication information.
Multimorbid patients ≥18 years, using a minimum of four regular medications from a minimum of two therapeutic medication classes were recruited from the Internal Medicine ward, Oslo University Hospital, Norway, from August 2014 to March 2016 and randomly assigned, 1:1, to the intervention or control group. Intervention patients received integrated medicines management throughout the hospital stay. Control patients received standard care. This paper reports the results of a prespecified secondary endpoint analysis of the randomized controlled trial; the difference between the intervention and control group in the quality of discharge medication information.
The analysis population comprised 384 patients. Integrated medicines management improved the discharge summary quality score of the medication information from 5.8 ± 1.5 to 8.6 ± 2.6 [mean difference 2.7, 95% confidence interval (CI) 2.3-3.2, P |
doi_str_mv | 10.1093/intqhc/mzae100 |
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Multimorbid patients ≥18 years, using a minimum of four regular medications from a minimum of two therapeutic medication classes were recruited from the Internal Medicine ward, Oslo University Hospital, Norway, from August 2014 to March 2016 and randomly assigned, 1:1, to the intervention or control group. Intervention patients received integrated medicines management throughout the hospital stay. Control patients received standard care. This paper reports the results of a prespecified secondary endpoint analysis of the randomized controlled trial; the difference between the intervention and control group in the quality of discharge medication information.
The analysis population comprised 384 patients. Integrated medicines management improved the discharge summary quality score of the medication information from 5.8 ± 1.5 to 8.6 ± 2.6 [mean difference 2.7, 95% confidence interval (CI) 2.3-3.2, P < .001]. In total, 171 intervention patients (89%) received a patient discharge information letter, compared to 66 control patients (35%), P < .001. The quality score of the medication information in the patient discharge information letter was improved from 6.0 ± 1.8 in the control group to 10.0 ± 1.3 in the intervention group (mean difference 4.0, 95% CI 3.6-4.4, P < .001).
Integrated medicines management delivered to multimorbid patients during a hospital stay improved the quality of the medication information in discharge summaries as well as patient discharge information letters and ensured that a discharge information letter in lay language was prepared for almost all patients who were involved in the management of their medications after discharge.</description><identifier>ISSN: 1353-4505</identifier><identifier>ISSN: 1464-3677</identifier><identifier>EISSN: 1464-3677</identifier><identifier>DOI: 10.1093/intqhc/mzae100</identifier><identifier>PMID: 39475049</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Medication Reconciliation - standards ; Middle Aged ; Multimorbidity ; Norway ; Original ; Patient Discharge ; Patient Safety</subject><ispartof>International journal for quality in health care, 2024-12, Vol.36 (4)</ispartof><rights>The Author(s) 2024. Published by Oxford University Press on behalf of International Society for Quality in Health Care.</rights><rights>The Author(s) 2024. Published by Oxford University Press on behalf of International Society for Quality in Health Care. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c276t-f9aaff9cf51ece96cc4ec562192b54de21d9c6a22fcac57d7087551f2bada6b73</cites><orcidid>0000-0002-6598-2215</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39475049$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mathiesen, Liv</creatorcontrib><creatorcontrib>Nguyen, Tram Bich Michelle</creatorcontrib><creatorcontrib>Dæhlen, Ingrid</creatorcontrib><creatorcontrib>Mowé, Morten</creatorcontrib><creatorcontrib>Lea, Marianne</creatorcontrib><title>Effect of integrated medicines management on quality of discharge medication information-a secondary endpoint in a randomized controlled trial</title><title>International journal for quality in health care</title><addtitle>Int J Qual Health Care</addtitle><description>High-quality discharge information is important to promote patient safety when patients are transferred from hospital to primary care. Patients with multiple long-term conditions are especially vulnerable to insufficient transfer of medication information, as they use many medications and have complex interactions with the healthcare services. The aim of this study was to investigate the effect of integrated medicines management provided to hospitalized multimorbid patients on the quality of the discharge medication information.
Multimorbid patients ≥18 years, using a minimum of four regular medications from a minimum of two therapeutic medication classes were recruited from the Internal Medicine ward, Oslo University Hospital, Norway, from August 2014 to March 2016 and randomly assigned, 1:1, to the intervention or control group. Intervention patients received integrated medicines management throughout the hospital stay. Control patients received standard care. This paper reports the results of a prespecified secondary endpoint analysis of the randomized controlled trial; the difference between the intervention and control group in the quality of discharge medication information.
The analysis population comprised 384 patients. Integrated medicines management improved the discharge summary quality score of the medication information from 5.8 ± 1.5 to 8.6 ± 2.6 [mean difference 2.7, 95% confidence interval (CI) 2.3-3.2, P < .001]. In total, 171 intervention patients (89%) received a patient discharge information letter, compared to 66 control patients (35%), P < .001. The quality score of the medication information in the patient discharge information letter was improved from 6.0 ± 1.8 in the control group to 10.0 ± 1.3 in the intervention group (mean difference 4.0, 95% CI 3.6-4.4, P < .001).
Integrated medicines management delivered to multimorbid patients during a hospital stay improved the quality of the medication information in discharge summaries as well as patient discharge information letters and ensured that a discharge information letter in lay language was prepared for almost all patients who were involved in the management of their medications after discharge.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medication Reconciliation - standards</subject><subject>Middle Aged</subject><subject>Multimorbidity</subject><subject>Norway</subject><subject>Original</subject><subject>Patient Discharge</subject><subject>Patient Safety</subject><issn>1353-4505</issn><issn>1464-3677</issn><issn>1464-3677</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNpVkU9vFDEMxUeIipbClSPKkcu0-TPJMCeEqrYgVeJSzpE3cXaDZpLdJIvUfgg-My67VHCKJf_y_OzXde8EvxB8Upcxtd3GXS6PgILzF92ZGMzQKzOOL6lWWvWD5vq0e13rD86FUdq86k7VNIyaD9NZ9-s6BHSN5cBICtcFGnq2oI8uJqxsgQRrXDARkthuD3NsD0-0j9VtoKzxAEOL1I8p5LL8qXtgFV1OHsoDw-S3mfQJYMAKJJ-X-EiDCGglzzOVrUSY33QnAeaKb4_veff95vr-6kt_9-3269Xnu97J0bQ-TAAhTC5ogQ4n49yAThspJrnSg0cp_OQMSBkcOD36kX8ctRZBrsCDWY3qvPt00N3uV-Tf0X4FZrstcSG_NkO0_3dS3Nh1_mkFnZArzknhw1Gh5N0ea7MLXQTnGRLmfbVKSEnXHrQi9OKAupJrLRie5whun1K0hxTtMUX68P5fd8_439jUb3uroW8</recordid><startdate>20241205</startdate><enddate>20241205</enddate><creator>Mathiesen, Liv</creator><creator>Nguyen, Tram Bich Michelle</creator><creator>Dæhlen, Ingrid</creator><creator>Mowé, Morten</creator><creator>Lea, Marianne</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6598-2215</orcidid></search><sort><creationdate>20241205</creationdate><title>Effect of integrated medicines management on quality of discharge medication information-a secondary endpoint in a randomized controlled trial</title><author>Mathiesen, Liv ; Nguyen, Tram Bich Michelle ; Dæhlen, Ingrid ; Mowé, Morten ; Lea, Marianne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c276t-f9aaff9cf51ece96cc4ec562192b54de21d9c6a22fcac57d7087551f2bada6b73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medication Reconciliation - standards</topic><topic>Middle Aged</topic><topic>Multimorbidity</topic><topic>Norway</topic><topic>Original</topic><topic>Patient Discharge</topic><topic>Patient Safety</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mathiesen, Liv</creatorcontrib><creatorcontrib>Nguyen, Tram Bich Michelle</creatorcontrib><creatorcontrib>Dæhlen, Ingrid</creatorcontrib><creatorcontrib>Mowé, Morten</creatorcontrib><creatorcontrib>Lea, Marianne</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal for quality in health care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mathiesen, Liv</au><au>Nguyen, Tram Bich Michelle</au><au>Dæhlen, Ingrid</au><au>Mowé, Morten</au><au>Lea, Marianne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of integrated medicines management on quality of discharge medication information-a secondary endpoint in a randomized controlled trial</atitle><jtitle>International journal for quality in health care</jtitle><addtitle>Int J Qual Health Care</addtitle><date>2024-12-05</date><risdate>2024</risdate><volume>36</volume><issue>4</issue><issn>1353-4505</issn><issn>1464-3677</issn><eissn>1464-3677</eissn><abstract>High-quality discharge information is important to promote patient safety when patients are transferred from hospital to primary care. Patients with multiple long-term conditions are especially vulnerable to insufficient transfer of medication information, as they use many medications and have complex interactions with the healthcare services. The aim of this study was to investigate the effect of integrated medicines management provided to hospitalized multimorbid patients on the quality of the discharge medication information.
Multimorbid patients ≥18 years, using a minimum of four regular medications from a minimum of two therapeutic medication classes were recruited from the Internal Medicine ward, Oslo University Hospital, Norway, from August 2014 to March 2016 and randomly assigned, 1:1, to the intervention or control group. Intervention patients received integrated medicines management throughout the hospital stay. Control patients received standard care. This paper reports the results of a prespecified secondary endpoint analysis of the randomized controlled trial; the difference between the intervention and control group in the quality of discharge medication information.
The analysis population comprised 384 patients. Integrated medicines management improved the discharge summary quality score of the medication information from 5.8 ± 1.5 to 8.6 ± 2.6 [mean difference 2.7, 95% confidence interval (CI) 2.3-3.2, P < .001]. In total, 171 intervention patients (89%) received a patient discharge information letter, compared to 66 control patients (35%), P < .001. The quality score of the medication information in the patient discharge information letter was improved from 6.0 ± 1.8 in the control group to 10.0 ± 1.3 in the intervention group (mean difference 4.0, 95% CI 3.6-4.4, P < .001).
Integrated medicines management delivered to multimorbid patients during a hospital stay improved the quality of the medication information in discharge summaries as well as patient discharge information letters and ensured that a discharge information letter in lay language was prepared for almost all patients who were involved in the management of their medications after discharge.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>39475049</pmid><doi>10.1093/intqhc/mzae100</doi><orcidid>https://orcid.org/0000-0002-6598-2215</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Aged Aged, 80 and over Female Humans Male Medication Reconciliation - standards Middle Aged Multimorbidity Norway Original Patient Discharge Patient Safety |
title | Effect of integrated medicines management on quality of discharge medication information-a secondary endpoint in a randomized controlled trial |
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