Prognosis and cardiotoxicity associated to adjuvant trastuzumab for breast cancer: real world study in a public health system

To analyze the prognosis of patients with breast cancer who developed trastuzumab-induced cardiotoxicity and to analyze factors associated with and resulting from cardiotoxicity. This was a retrospective cohort study that included 255 HER2-positive breast cancer patients who received adjuvant trastu...

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Bibliographic Details
Published in:Revista Brasileira de ginecologia e obstetrícia 2024, Vol.46
Main Authors: Cabello, Ana Elisa Ribeiro da Silva, Cabello, César, Ramalho, Susana Oliveira Botelho, Coelho, Otávio Rizzi, Coelho-Filho, Otávio Rizzi, Machado, Helymar da Costa, Conde, Délio Marques, Zeferino, Luiz Carlos
Format: Article
Language:English
Subjects:
Adult
Aged
Antineoplastic Agents, Immunological - adverse effects
Breast Neoplasms - drug therapy
Cardiotoxicity - etiology
Chemotherapy, Adjuvant - adverse effects
Cohort Studies
Female
Humans
Middle Aged
Original
Prognosis
Public Health
Retrospective Studies
Trastuzumab - adverse effects
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Summary:To analyze the prognosis of patients with breast cancer who developed trastuzumab-induced cardiotoxicity and to analyze factors associated with and resulting from cardiotoxicity. This was a retrospective cohort study that included 255 HER2-positive breast cancer patients who received adjuvant trastuzumab therapy. The inclusion criteria were a diagnosis of HER2-positive breast cancer and adjuvant trastuzumab therapy; disease stage I-III;
ISSN:1806-9339
0100-7203
1806-9339
DOI:10.61622/rbgo/2024rbgo93