A Case of Rapidly Progressive Glomerulonephritis Associated With Metastatic Melanoma

Pauci-immune glomerulonephritis is a rapidly progressive form of glomerulonephritis. It is distinguished from other rapidly progressive glomerular diseases by the lack of immune deposits seen on renal biopsy, hence the name "pauci-immune." We present a case of pauci-immune glomerulonephrit...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-11, Vol.16 (11), p.e73703
Main Authors: Rao, Sitara, Ahmed, Moeed, Ahmed, Abdul R, Brown, Julia
Format: Article
Language:English
Subjects:
Internal Medicine
Nephrology
Oncology
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Summary:Pauci-immune glomerulonephritis is a rapidly progressive form of glomerulonephritis. It is distinguished from other rapidly progressive glomerular diseases by the lack of immune deposits seen on renal biopsy, hence the name "pauci-immune." We present a case of pauci-immune glomerulonephritis in a patient with a history of malignancy that was treated with chemotherapy. Notably, the presentation of kidney injury coincided with the discovery of a new metastasis. Prompt treatment of glomerulonephritis is critically important to preserve renal function, though the optimal treatment strategy may not be straightforward in a patient with coexisting malignancy. Ultimately, this case illustrates that collaboration between patients, medical teams, and families is needed to optimize treatment strategy in unique circumstances.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.73703