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Lung Disease in Sjögren's Syndrome: Insights From a Reference Center's Population

Background Sjögren's syndrome (SS) is a chronic systemic autoimmune disorder characterized by lymphocytic infiltration of the exocrine glands. Although primarily affecting these glands, the syndrome can also involve several organs. Interstitial lung disease is one of the most severe complicatio...

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Published in:Curēus (Palo Alto, CA) CA), 2024-11, Vol.16 (11), p.e73734
Main Authors: Silva Araújo, Catarina, Laranjeira, Francisco, Simão de Magalhães, Mariana, Oliveira, Ana, Vale, Martinha M, Furtado, Inês, Farinha, Fátima, Brandão, Mariana, Valadão, Ivone
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Language:English
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Summary:Background Sjögren's syndrome (SS) is a chronic systemic autoimmune disorder characterized by lymphocytic infiltration of the exocrine glands. Although primarily affecting these glands, the syndrome can also involve several organs. Interstitial lung disease is one of the most severe complications associated with SS. Objectives This study aims to analyze the characteristics of lung involvement in patients with primary SS from a reference medical center's population. Methods Retrospective, longitudinal study of primary SS patients diagnosed until December 2022. Clinical and laboratory data were collected and subjected to statistical analysis using SPSS®. A 95% confidence interval was considered, with statistical significance set at p
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.73734