Follicular Lymphoma Presenting as a Primary Omental Mass: A Case Report and Pathological Analysis

Follicular lymphoma (FL) is a gradually progressing type of B-cell non-Hodgkin lymphoma (NHL), distinguished by its characteristic follicular pattern of growth and a typically indolent clinical course. It is identified by the abnormal growth of B-cells in the lymph nodes. We report a case of a 45-ye...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-11, Vol.16 (11), p.e73810
Main Authors: Raman, Srinivasan, Amitkumar, Kalaivani, Radhakrishnan, Balaji, Kumaran, Subhalakshmi
Format: Article
Language:English
Subjects:
Hematology
Medical Education
Pathology
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Summary:Follicular lymphoma (FL) is a gradually progressing type of B-cell non-Hodgkin lymphoma (NHL), distinguished by its characteristic follicular pattern of growth and a typically indolent clinical course. It is identified by the abnormal growth of B-cells in the lymph nodes. We report a case of a 45-year-old female who came up with complaints of heavy menstrual bleeding and easy fatiguability. Imaging studies revealed an accidental finding of a primary mesenteric mass. Infracolic omentectomy and a bilateral pelvic lymph node dissection were done, and the specimen was sent for histopathological examination. Microscopic examination of the omental mass revealed a nodular growth pattern with prominent follicular structures composed of centrocytes and scattered centroblasts. Immunohistochemical staining demonstrated positivity for cluster of differentiation 20 (CD20), CD10, and B-cell lymphoma 2 (BCL2), confirming the diagnosis of FL. Thus, we report this rare manifestation of FL presenting as an isolated omental mass.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.73810